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科研机构
上海药物研究所 [130]
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期刊论文 [126]
会议论文 [4]
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2021 [3]
2020 [6]
2019 [7]
2018 [17]
2017 [12]
2016 [12]
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Chemistry [1]
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Identification and mechanistic analysis of an inhibitor of the CorC Mg2+ transporter
期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 4, 页码: 38
作者:
Huang, Yichen
;
Mu, Kaijie
;
Teng, Xinyu
;
Zhao, Yimeng
;
Funato, Yosuke
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/08/17
Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure
期刊论文
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2021, 卷号: 10, 期号: 6, 页码: 33
作者:
Li, Xuan
;
Lu, Qingguo
;
Qiu, Yunguang
;
do Carmo, Jussara M.
;
Wang, Zhen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
cardiac hypertrophy
cardiac metabolism
cardiomyocytes
sodium glucose cotransporter 2
transverse aortic constriction
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
Synthetic antibodies against BRIL as universal fiducial marks for single?particle cryoEM structure determination of membrane proteins
期刊论文
naturecommunications, 2020, 卷号: 11, 期号: 1, 页码: 1
作者:
Somnath Mukherjee
;
Satchal K. Erramilli
;
Mark Ammirati
;
Frances J. D. Alvarez
;
Kimberly F. Fennell
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1
作者:
Mukherjee, Somnath
;
Erramilli, Satchal K
;
Ammirati, Mark
;
Alvarez, Frances J D
;
Fennell, Kimberly F
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2021/12/01
Current trends in drug metabolism and pharmacokinetics
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
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