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科研机构
上海药物研究所 [47]
内容类型
期刊论文 [46]
学位论文 [1]
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2021 [3]
2020 [3]
2019 [1]
2018 [1]
2017 [1]
2016 [3]
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Biotechnol... [2]
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Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhang, Wan-ting
;
Liu, Ting-ting
;
Wu, Man
;
Chen, Xiao-chen
;
Han, Li
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
nanobody
FGL1
cancer immunology
diagnosis
immune checkpoint
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis
期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:
Zhang, Linqiang
;
Zhang, Zhiguo
;
Li, Chengbin
;
Zhu, Tingting
;
Gao, Jing
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
NAFLD
S100A11
FOXO1
Autophagy
Lipid Metabolism
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes
期刊论文
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:
Dou, Hui-Xia
;
Wang, Ting
;
Su, Hai-Xia
;
Gao, Ding-Ding
;
Xu, Ye-Chun
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
eFABP4
Adipocyte
Differentiation
Lipolysis
Inflammation
A new recombinant MS-superoxide dismutase alleviates 5-fluorouracil-induced intestinal mucositis in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 348-357
作者:
Yan, Xiao-xia
;
Li, Hai-long
;
Zhang, Yi-ting
;
Wu, Shou-yan
;
Lu, Heng-lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
anewrecombinantmssuperoxidedismutasealleviates5fluorouracilinducedintestinalmucositisinmice
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 348
作者:
Yan Xiaoxia
;
Li Hailong
;
Zhang Yiting
;
Wu Shouyan
;
Lu Henglei
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 26, 页码: 23018-23025
作者:
Zhang, Yu
;
Zhang, Yujie
;
Guo, Qin
;
Guo, Zhongyuan
;
Chen, Xinli
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  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
macromolecular protein delivery
cell vector
tumor targeting
intratumoral drug distribution
breast cancer therapy
Wnt7a activates canonical Wnt signaling, promotes bladder cancer cell invasion, and is suppressed by miR-370-3p
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 18, 页码: 6693-6706
作者:
Huang, Xiaojing
;
Zhu, Hongwen
;
Gao, Zemin
;
Li, Junzun
;
Zhuang, Junlong
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Wnt signaling
cancer biology
invasion
mass spectrometry (MS)
microRNA (miRNA)
metalloprotease
bladder cancer
miR-370-3p
MMP10
Wnt7a
Establishment of a reporter gene system for activity detection of hepatocyte nuclear factor 4alpha
期刊论文
Academic Journal of Second Military Medical University, 2017, 卷号: 38, 期号: 9, 页码: 1112-1118
作者:
Sun Bingjie
;
Chen Shijie
;
Deng Longfei
;
Ding Chenhong
;
Chen Fei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Ninjurin 1
hepatocyte nuclear factor 4alpha
Ninjurin 1
reporter gene system
small molecular compound
Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting beta 1 subunit expression and disrupting proteasome assembly
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 908-918
作者:
Sun, Peng
;
Feng, Li-xing
;
Zhang, Dong-mei
;
Liu, Miao
;
Liu, Wang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
bufalin
ChanSu
cardiac steroids
proteasome beta 1 subunit
proteasome assembly
A549 human lung cancer cells
proteomics
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