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CORC

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SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：58/0  |  提交时间：2020/12/24
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56
作者:  Huang, Suling;  Ma, Shanyao;  Ning, Mengmeng;  Yang, Wenji;  Ye, Yangliang
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
Alogliptin alleviates liver fibrosis via suppression of activated hepatic stellate cell 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 511, 期号: 2, 页码: 387-393
作者:  Zhang, Hanyan;  Sun, Dandan;  Wang, Guanzhen;  Cui, Shichao;  Field, Robert A.
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min
收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Xie, Wei;  Ye, Yangliang;  Feng, Ying;  Xu, Tifei;  Huang, Suling
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:  Ma, Shan-yao;  Ning, Meng-meng;  Zou, Qing-an;  Feng, Ying;  Ye, Yang-liang
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Cao, Hua;  Chen, Zhi-Xiang;  Wang, Kai;  Ning, Meng-Meng;  Zou, Qing-An
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2) 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 2, 页码: 747-751
作者:  Zhan, Yang;  Zhang, Xiao-Wei;  Xiong, Ying;  Li, Bo-Liang;  Nan, Fa-Jun
收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08

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