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科研机构
上海药物研究所 [24]
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期刊论文 [24]
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2021 [1]
2020 [1]
2018 [3]
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Macrophage polarization: an effective approach to targeted therapy of inflammatory bowel disease
期刊论文
EXPERT OPINION ON THERAPEUTIC TARGETS, 2021, 页码: 19
作者:
Du, Yaoyao
;
Rong, Lan
;
Cong, Yuanhua
;
Shen, Lan
;
Zhang, Ning
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2021/05/24
Inflammatory bowel disease
macrophage polarization
immune regulation
targeted therapy
New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their alpha-glucosidase inhibitory activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 页码: 6
作者:
Wu, Meng-Jun
;
Wang, Hong
;
Jiang, Cheng-Shi
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/05/24
Sinularia crassa
Cembranoid
Modified Mosher's method
ECD calculation
alpha-Glucosidase inhibitor
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine
期刊论文
MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52
作者:
Li, Hong
;
Zhao, Lihua
;
Singh, Rani
;
Ham, J. Nina
;
Fadoju, Doris O.
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
Glucagon receptor
Newborn screening
GCGR mutation
Hyperaminoacidemia
Mahvash disease
Pancreatic alpha cell hyperplasia (ACH)
Pancreatic neuroendocrine tumor (PNET)
Species-Specific Involvement of Integrin alpha IIb beta 3 in a Monoclonal Antibody CH12 Triggers Off-Target Thrombocytopenia in Cynomolgus Monkeys
期刊论文
MOLECULAR THERAPY, 2018, 卷号: 26, 期号: 6, 页码: 1457-1470
作者:
Zhang, Yiting
;
Sun, Jianhua
;
Tan, Minjia
;
Liu, Yongzhen
;
Li, Qian
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Tumor suppressive role of rottlerin in cancer therapy
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 11, 页码: 3345-3356
作者:
Ma, Jia
;
Hou, Yingying
;
Xia, Jun
;
Zhu, Xueqiong
;
Wang, Z. Peter
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Rottlerin
cancer
therapy
target
antitumor
Sarcophytrols G - L, Novel Minor Metabolic Components from South China Sea Soft Coral Sarcophyton trocheliophorum MARENZELLER
期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 6
作者:
Liang, Lin-Fu
;
Chen, Wen-Ting
;
Mollo, Ernesto
;
Yao, Li-Gong
;
Wang, He-Yao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Terpenoids
Soft coral
Sarcophyton trocheliophorum
Structure elucidation
PTP1B inhibitory activities
Current situation of immuno-oncology development
期刊论文
Science & Technology Review, 2017, 卷号: 35, 期号: 13, 页码: 61-65
作者:
Mao Yanyan
;
Huang Yaoqing
;
Gao Liubin
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
anti-tumor
immuno-oncology
CAR-T cell therapy
Advances in Small-Molecule GPR40 Agonists for Treatment of Type 2 Diabetes Mellitus
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 4, 页码: 736-743
作者:
Li He
;
Long Yaqiu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
type II diabetes mellitus
GPR40
agonists
glucose-stimulated insulin secretion
phenylpropanoic acid
A new bioactive steroidal ketone from the South China Sea sponge Xestospongia testudinaria
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2016, 卷号: 18, 期号: 2, 页码: 195-199
作者:
He, Wen-Fei
;
Xue, Duo-Qing
;
Yao, Li-Gong
;
Li, Jia
;
Liu, Hai-Li
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
PTP1B inhibitory activity
Xestospongia testudinaria
sponge
Petrosiidae
steroidal ketone
An analysis on global drug development status of rheumatoid arthritis
期刊论文
Science & Technology Review, 2016, 卷号: 34, 期号: 24, 页码: 44-56
作者:
Liu Lili
;
Mao Yanyan
;
Gao Liubin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
rheumatoid arthritis
autoimmune disease
biological agents
small molecule drugs
tumor necrosis factor
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