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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
发表日期
2021 [1]
2020 [3]
2019 [2]
2018 [1]
2017 [1]
2001 [1]
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Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557
作者:
He, Yisheng
;
Zhang, Wei
;
Ma, Jiang
;
Xia, Qingsu
;
Song, Zijing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Wu, Shou-yan
;
Wang, Wen-jie
;
Dou, Jin-hui
;
Gong, Li-kun
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
18 beta-glycyrrhetic acid
licorice preparation
liver injury
glycyrrhetinic acid target
Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-kappa B/IL-6/STAT3 Signaling Pathway
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 2, 页码: 677-687
作者:
Wu, Jia-Sheng
;
Liu, Qian
;
Fang, Shan-Hua
;
Liu, Xing
;
Zheng, Min
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
intrahepatic cholestasis
Huangqi decoction
proteomics
NF-kappa B
IL-6
STAT3
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 1: Metabolic profiles from the liver-centric perspective
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 237, 页码: 81-91
作者:
Liu, Huan
;
Chen, Mingcang
;
Yin, Hao
;
Hu, Pei
;
Wang, Yangyang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Yin-chen-hao tang
Liver
Metabolites
Liver injury
HPLC-Q-TOF
Carbon tetrachloride
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 236, 页码: 161-172
作者:
Tian, Xiaoting
;
Liu, Huan
;
Qiao, Shida
;
Yin, Hao
;
Chen, Mingcang
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Hepatic disposition
Pharmacokinetics
Hepatoprotection
HepG2
Carbon tetrachloride
metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923
作者:
Xie Yang
;
Zhou Xu
;
Pei Hu
;
Chen Mingcang
;
Sun Zhaolin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
B-II
LIVER-INJURY
IN-VITRO
ANEMARRHENA-ASPHODELOIDES
OXIDATIVE STRESS
RAT PLASMA
A-III
MANGIFERIN
NORATHYRIOL
EXTRACT
Zhimu
timosaponin A3
mangiferin
pharmacokinetics
metabolism
hepatotoxicity
antioxidant
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Effects of salviainolic acid A (SA-A) on liver injury: SA-A action on hepatic peroxidation
期刊论文
LIVER, 2001, 卷号: 21, 期号: 6, 页码: 384-390
作者:
Liu, P
;
Hu, YY
;
Liu, CH
;
Liu, C
;
Zhu, DY
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
ALT
AST
carbon tetrachloride
catalase (CAT)
glutathione (GSH)
glutathione peroxidase (GSH-PX)
hepatocyte
lactase dehydrogenase (LDH)
lipid peroxidation
liver fibrosis
liver injury
malondiadehyde (MDA)
salviainolic acid A
superoxide dismutase (SOD)
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