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CORC

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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：25/0  |  提交时间：2022/01/18
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei
收藏  |  浏览/下载：19/0  |  提交时间：2022/01/04
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01
Transfersomes improved delivery of ascorbic palmitate into the viable epidermis for enhanced treatment of melasma 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 608, 页码: 10
作者:  Li, Junjun;  Duan, Nianxiu;  Song, Sha;  Nie, Di;  Yu, Miaorong
收藏  |  浏览/下载：69/0  |  提交时间：2021/11/04
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian
收藏  |  浏览/下载：99/0  |  提交时间：2021/11/04
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Picomolar antimalarial agent from a Chinese medicinal plant 期刊论文
SCIENCE CHINA-CHEMISTRY, 2021, 页码: 5
作者:  Zhou, Bin;  Zimbres, Flavia M.;  Butler, Joshua H.;  Xu, Cheng-Hui;  Haney, Reagan S.
收藏  |  浏览/下载：62/0  |  提交时间：2021/12/01
CsCCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 39, 页码: 11626-11636
作者:  Liang, Nan;  Yao, Ming-Dong;  Wang, Ying;  Liu, Jia;  Feng, Lu
收藏  |  浏览/下载：20/0  |  提交时间：2021/12/01
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu
收藏  |  浏览/下载：41/0  |  提交时间：2021/12/01

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