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Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载:27/0  |  提交时间:2022/01/04
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao
收藏  |  浏览/下载:36/0  |  提交时间:2022/01/04
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载:17/0  |  提交时间:2021/12/16
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 期刊论文
CELL RESEARCH, 2021, 页码: 3
作者:  Xie, Yuanchao;  Yin, Wanchao;  Zhang, Yumin;  Shang, Weijuan;  Wang, Zhen
收藏  |  浏览/下载:109/0  |  提交时间:2021/11/04
Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/04
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:35/0  |  提交时间:2021/11/04
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载:46/0  |  提交时间:2021/08/17
Insights into Optical Probes Based on Aggregation-Induced Emission: from Restriction of Intramolecular Motions to Dark State 期刊论文
ADVANCED OPTICAL MATERIALS, 2021, 页码: 9
作者:  Huang, Shuai;  Ding, Jipeng;  Bi, Anyao;  Yu, Kunqian;  Zeng, Wenbin
收藏  |  浏览/下载:55/0  |  提交时间:2021/11/04
Metal-organic frameworks for advanced drug delivery 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 8, 页码: 2362-2395
作者:  He, Siyu;  Wu, Li;  Li, Xue;  Sun, Hongyu;  Xiong, Ting
收藏  |  浏览/下载:44/0  |  提交时间:2021/11/04
Synthesis and biological evaluation of novel cabazitaxel analogues 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 41, 页码: 12
作者:  Ren, Sumei;  Zhang, Minmin;  Wang, Yujie;  Guo, Jia;  Wang, Junfei
收藏  |  浏览/下载:60/0  |  提交时间:2021/08/17


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