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科研机构
上海药物研究所 [28]
内容类型
期刊论文 [28]
发表日期
2021 [3]
2020 [2]
2019 [2]
2017 [2]
2016 [6]
2015 [2]
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Multiscale modelling of cerebrovascular injury reveals the role of vascular anatomy and parenchymal shear stresses
期刊论文
SCIENTIFIC REPORTS, 2021, 卷号: 11, 期号: 1, 页码: 12
作者:
Khosroshahi, Siamak Farajzadeh
;
Yin, Xianzhen
;
Donat, Cornelius K.
;
McGarry, Aisling
;
Lopez, Maria Yanez
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/08/17
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yi-fei
;
Zhang, Lei
;
Wu, Qi
;
Feng, Lin-yin
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
ischemic brain injury
paeoniflorin
MCAO
HDAC4
cytochrome c
apoptosis
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yi-fei
;
Zhang, Lei
;
Wu, Qi
;
Feng, Lin-yin
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/06/11
ischemic brain injury
paeoniflorin
MCAO
HDAC4
cytochrome c
apoptosis
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59, 期号: 6, 页码: 2429-2439
作者:
Gao, Cheng-Long
;
Hou, Gui-Ge
;
Liu, Jin
;
Ru, Tong
;
Xu, Ya-Zhou
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
anti-inflammatory
drug discovery
heterocycles
photoaffinity labeling
proteins
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:
Zhang, Ning
;
Han, Li
;
Xue, Yaru
;
Deng, Qiangqiang
;
Wu, Zhitao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
magnesium lithospermate B
hepatic ischemia/reperfusion
acute injury
anti-inflammation
Jak2/Stat3 signaling pathway
A UPLC/MS/MS method for determination of protosappanin B in rat plasma and its application of a pharmacokinetic and bioavailability study
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2017, 卷号: 31, 期号: 7
作者:
Chen, Wei-Ying
;
Zhou, Xian-Zhen
;
Wu, Li-Lan
;
Wu, Yun-Shan
;
Wang, Shu-Mei
收藏
  |  
浏览/下载:228/0
  |  
提交时间:2019/01/08
Bioavailability
Pharmacokinetic
protosappanin B
UPLC-MS/MS
Dual anti-ischemic effects of rosmarinic acid n-butyl ester via alleviation of DAPK-p53-mediated neuronal damage and microglial inflammation
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 459-468
作者:
Wu, Lei
;
Wang, Hong-min
;
Li, Jin-long
;
Feng, Hong-xuan
;
Zhao, Wei-min
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
cerebral ischemia
rosmarinic acid n-butyl ester
SH-SY5Y neuroblastoma cells
apoptosis
death-associated protein kinase
p53
microglia
inflammation
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells
期刊论文
BRAIN RESEARCH, 2016, 卷号: 1649, 页码: 123-131
作者:
Hu, Yang-ye
;
Wang, Yuan
;
Liang, Shuang
;
Yu, Xue-li
;
Zhang, Lei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Senkyunolide I
Microglial cells
Oxygen-glucose deprivation/reoxygenation
TLR4/NF-kappa B pathway
HSF-1/Hsp70
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