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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载:37/0  |  提交时间:2021/12/01
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24
Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin 期刊论文
STEROIDS, 2020, 卷号: 164, 页码: 11
作者:  Zhou, Yang;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia;  Lei, Min
收藏  |  浏览/下载:42/0  |  提交时间:2021/05/24
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase 期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:  Butler, Joshua H.;  Baptista, Rodrigo P.;  Valenciano, Ana L.;  Zhou, Bin;  Kissinger, Jessica C.
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/24
Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 15, 页码: 8442-8457
作者:  Yang, Teng;  Zhang, Tao;  Guan, Xiang-Na;  Dong, Ze;  Lan, Lefu
收藏  |  浏览/下载:21/0  |  提交时间:2020/12/24
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:  Niu, Ao;  Wang, Yang;  Yang, Yushe;  Wei, Jianhai;  Ding, Jian
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:  Ma, Fei;  Liu, Jian;  Zhou, Tingting;  Lei, Min;  Chen, Jing
收藏  |  浏览/下载:79/0  |  提交时间:2019/01/08
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 235-251
作者:  Wei, Hanwen;  Mao, Fei;  Ni, Shuaishuai;  Chen, Feifei;  Li, Baoli
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08


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