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科研机构
上海药物研究所 [168]
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期刊论文 [168]
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2021 [7]
2020 [7]
2019 [6]
2018 [16]
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Pharmacolo... [2]
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Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling
期刊论文
ONCOGENE, 2021, 页码: 10
作者:
Kong, Ya
;
Zhang, Yutian
;
Wang, Hanlin
;
Kan, Weijuan
;
Guo, Haoran
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 100, 页码: 12
作者:
Wang, Lan
;
Zhao, Danfeng
;
Wang, Huan
;
Wang, Lele
;
Liu, Xiaohui
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/12/01
Inflammation
Microglia
LPS
RNA-seq
JAK
STAT signaling pathway
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/04
Acyl-CoA oxidase ACOX-1 interacts with a peroxin PEX-5 to play roles in larval development of Haemonchus contortus
期刊论文
PLOS PATHOGENS, 2021, 卷号: 17, 期号: 7, 页码: 21
作者:
Shi, Hengzhi
;
Huang, Xiaocui
;
Chen, Xueqiu
;
Yang, Yi
;
Wang, Zhao
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
Histamine activates HinK to promote the virulence of Pseudomonas aeruginosa
期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 11, 页码: 1101-1118
作者:
Wang, Yaya
;
Cao, Qiao
;
Cao, Qin
;
Gan, Jianhua
;
Sun, Ning
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Pseudomonas aeruginosa
Histamine
Metabolism
Host-microbe interaction
Virulence
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:
Liu, Na
;
Yang, Rui
;
Shi, Ying
;
Chen, Ling
;
Liu, Yating
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/21
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus
期刊论文
MOLECULAR MICROBIOLOGY, 2020, 页码: 20
作者:
Yang, Nana
;
Cao, Qiao
;
Hu, Shuyang
;
Xu, Chenchen
;
Fan, Ke
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2020/07/01
ClpXP
microbial interspecies interactions
proteolysis
Pseudomonas aeruginosa
quorum sensing
An in vitro Fo''rster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Wang, Yu-zhe
;
Liu, Xiao
;
Way, George
;
Madarha, Vipul
;
Zhou, Qing-tong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
SUMOylation inhibitor
WNN0605-F008
high-throughput screening
Ubc9
PIAS1
Fo''rster resonance energy transfer
surface plasmon resonance
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