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CORC

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Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
TTC7 and Hyccin Regulate Neuronal A beta(42) Accumulation and its Associated Neural Deficits in A beta(42)-Expressing Drosophila 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2018, 卷号: 65, 期号: 3, 页码: 1001-1010
作者:  Sun, Minghao;  Zhao, Yinghui;  Han, Men;  Zhang, Baozhu;  Zhang, Xiao
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention 期刊论文
actapharmaceuticasinicab, 2018, 卷号: 000, 期号: 005, 页码: 767
作者:  Basnet Rajesh;  Gong Grace Qun;  Li Chenyao;  Wang Mingwei
收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01
SGK  AKT  PI3K  Cancer  Signalling  Kinase  Inhibitor  
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 489, 期号: 1, 页码: 14-20
作者:  Wang, Hongbin;  Quan, Haitian;  Lou, Liguang
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
SP6616 as a new Kv2.1 channel inhibitor efficiently promotes beta-cell survival involving both PKC/Erk1/2 and CaM/PI3K/Akt signaling pathways 期刊论文
CELL DEATH & DISEASE, 2016, 卷号: 7
作者:  Zhou, T. T.;  Quan, L. L.;  Chen, L. P.;  Du, T.;  Sun, K. X.
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen, Hongbo;  Zeng, Xiaobin;  Gao, Chunmei;  Ming, Pinghong;  Zhang, Jianping
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474
作者:  Chen, Si-Meng;  Guo, Chen-Liang;  Shi, Jia-Jie;  Xu, Yi-Chao;  Chen, Yi
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
DW09849, a Selective Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Prevents PI3K Signaling and Preferentially Inhibits Proliferation of Cells Containing the Oncogenic Mutation p110 alpha (H1047R) 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 348, 期号: 3, 页码: 432-441
作者:  Liu, Jia-li;  Gao, Guo-rui;  Zhang, Xi;  Cao, Su-fen;  Guo, Chen-liang
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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