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科研机构
上海药物研究所 [19]
内容类型
期刊论文 [19]
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2021 [3]
2020 [7]
2019 [1]
2018 [3]
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2015 [2]
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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/16
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 181, 页码: 357-368
作者:
Guo, Ciliang
;
Wang, Yeqing
;
Zhang, Shihai
;
Zhang, Xiuqi
;
Du, Zhenyun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
pinnatifida polysaccharide
Colitis
Gut microbiota
Short chain fatty acids
Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 10, 页码: 1966-1976
作者:
Zhao, Yuge
;
Yang, Yuting
;
Zhang, Jiaxin
;
Wang, Rong
;
Cheng, Biyun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Targeting delivery
Macrophages
Patchouli alcohol
Liposome
Inflammatory bowel disease
Colitis
Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Ning, Meng-meng
;
Yang, Wen-ji
;
Guan, Wen-bo
;
Gu, Yi-pei
;
Feng, Ying
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
ulcerative colitis
dextran sulfate sodium
dipeptidyl peptidase 4
sitagliptin
glucagon-like peptide-2
GLP-2(3-33)
apoptosis
proliferation
Patchouli Alcohol: a Natural Sesquiterpene Against Both Inflammation and Intestinal Barrier Damage of Ulcerative Colitis
期刊论文
INFLAMMATION, 2020, 页码: 13
作者:
Wu, Zhuona
;
Zeng, Hairong
;
Zhang, Lili
;
Pu, Yiqiong
;
Li, Suyun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
patchouli alcohol
ulcerative colitis
intestinal integrity
anti-inflammatory
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 4, 页码: 17
作者:
Li, Heng
;
Feng, Chunlan
;
Fan, Chen
;
Yang, Yang
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way
期刊论文
FASEB JOURNAL, 2020, 页码: 16
作者:
Wu, Yanwei
;
Wu, Bing
;
Zhang, Zongwang
;
Lu, Huimin
;
Fan, Chen
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
IBD
M1
M2
ulcerative colitis
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 447-461
作者:
Li, Heng
;
Fan, Chen
;
Lu, Huimin
;
Feng, Chunlan
;
He, Peilan
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Ulcerative colitis
Berberine
Mucosal inflammation
Enteric glial cells
Enteric nervous system
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
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