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科研机构
上海药物研究所 [120]
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期刊论文 [120]
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2022 [1]
2021 [3]
2020 [13]
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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 卷号: 57, 期号: 91, 页码: 12098-12110
作者:
Tong, Pei-Hong
;
Zhu, Ling
;
Zang, Yi
;
Li, Jia
;
He, Xiao-Peng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/12/16
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 18
作者:
Bernasocchi, Tiziano
;
El Tekle, Geniver
;
Bolis, Marco
;
Mutti, Azzurra
;
Vallerga, Arianna
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  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020)
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:
Wu, Jingwei
;
Zhang, Huan
;
Zhao, Guilong
;
Wang, Runling
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  |  
浏览/下载:65/0
  |  
提交时间:2021/08/17
SHP2 inhibitor
PTPN11 gene
allosteric
cancer
combination therapy
clinical trial
Combinatorial Photothermal 3D-Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 14
作者:
He, Chao
;
Yu, Luodan
;
Yao, Heliang
;
Chen, Yu
;
Hao, Yongqiang
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  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
bone metastasis
breast cancer
checkpoint blockade
immunotherapy
osteogenesis
photothermal therapy
Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer
期刊论文
BIOMATERIALS, 2020, 卷号: 255, 页码: 12
作者:
He, Chao
;
Yu, Luodan
;
Ding, Li
;
Yao, Heliang
;
Chen, Yu
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  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
Silicene
Epigenetics
KDM3A
p53
Photothermal therapy
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:
Liu, Na
;
Yang, Rui
;
Shi, Ying
;
Chen, Ling
;
Liu, Yating
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  |  
浏览/下载:32/0
  |  
提交时间:2020/12/21
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
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  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 321, 页码: 483-496
作者:
Sun, Tao
;
Zhang, Guangping
;
Guo, Zhongyuan
;
Chen, Qinjun
;
Zhang, Yujie
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Cu chelator
Antiangiogenesis
Theranostic
Real-time reporting
Co-delivery
Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1051-1059
作者:
Zhu, Qiwen
;
Saeed, Madiha
;
Song, Rundi
;
Sun, Tao
;
Jiang, Chen
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  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Cancer therapy
Drug delivery systems
Dynamic covalent chemistry
Acid-responsive
Reduction-responsive
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