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期刊论文 [203]
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Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
期刊论文
FRONTIERS IN PSYCHIATRY, 2022, 卷号: 12, 页码: 9
作者:
Liu, Dianying
;
Liu, Shaohua
;
Xiu, Meihong
;
Deng, Hongdong
;
Guo, Huiyun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/02/28
schizophrenia
sexual dysfunction
pleasure
arousal
motivation
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Pao Pereira Extract Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by inhibiting 5 alpha-Reductase
期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 10
作者:
Liu, Jiakuan
;
Fang, Tian
;
Li, Meiqian
;
Song, Yuting
;
Li, Junzun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Zhen
;
Jiang, Xiangrui
;
Zhang, Xianglei
;
Tian, Guanghui
;
Yang, Rulei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2019/06/28
MicroRNA-205 is associated with diabetes mellitus-induced erectile dysfunction via down-regulating the androgen receptor
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 5
作者:
Wen, Yan
;
Liu, Guohui
;
Zhang, Yun
;
Li, Hai
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
androgen receptor
apoptosis
erectile dysfunction
microRNA-205
proliferation
Inactivation of the Ras/MAPK/PPAR signaling axis alleviates diabetic mellitus-induced erectile dysfunction through suppression of corpus cavernosal endothelial cell apoptosis by inhibiting HMGCS2 expression
期刊论文
ENDOCRINE, 2019, 卷号: 63, 期号: 3
作者:
Zhang, Zhuo
;
Li, Hai
;
Zhang, Ying
;
Zhang, Hai-Yan
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  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Diabetic mellitus-induced erectile dysfunction
Corpus cavernosal endothelial cells
Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2
Ras
MAPK
PPAR signaling axis
Apoptosis
MyD88 overexpression deteriorates Ang-II-induced ED via upregulating MPO and COX2 and downregulating eNOS in the corpus cavernosum of rats
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 5
作者:
Zhang, Haishan
;
Zhang, Shujuan
;
Jia, Linpei
;
Li, Hai
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Ang-II
corpus cavernosum penises
endothelial cells
erectile dysfunction
MyD88
oxidative stress
TLR4
Silencing Nogo-B receptor inhibits penile corpus cavernosum vascular smooth muscle cell apoptosis of rats with diabetic erectile dysfunction by down-regulating ICAM-1
期刊论文
PLOS ONE, 2019, 卷号: 14, 期号: 8
作者:
Zhang, Yun
;
Wen, Yan
;
Li, Hai
;
Huo, Wei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/05
Downregulated lncRNA-MIAT confers protection against erectile dysfunction by downregulating lipoprotein lipase via activation of miR328a-5p in diabetic rats
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2019, 卷号: 1865, 期号: 6
作者:
Li, Yang
;
Huo, Wei
;
Hou, Yi
;
Li, Hai
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Diabetes
Erectile dysfunction
microRNA-328a-5p
Long noncoding
RNA myocardial infarction associated
transcript
Lipoprotein lipase
Smooth muscle cells
Endothelial cells
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