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浏览/检索结果: 共17条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu 收藏  |  浏览/下载：52/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9 作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi 收藏  |  浏览/下载：64/0  |  提交时间：2020/12/24 Ubiquitination  High throughput screening  Drug discovery  USP8   USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文 FEBS JOURNAL, 2020, 页码: 18 作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying 收藏  |  浏览/下载：87/0  |  提交时间：2020/12/24 colorectal cancer  HDX-MS  inhibitor  USP25  USP28  Vismodegib   Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 100, 页码: 8 作者:  Hou, Hui;  Yang, Ruirui;  Liu, Xiaohong;  Wu, Xiaolong;  Zhang, Sulin 收藏  |  浏览/下载：3/0  |  提交时间：2020/12/24 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X. 收藏  |  浏览/下载：103/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10 作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 Histone methylation  SET7  Small-molecule inhibitor  Virtual screening  Molecular probe   CRISPR-cas9: a powerful tool towards precision medicine in cancer treatment 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 5, 页码: 583-587 作者:  Xing, Hui;  Meng, Ling-hua 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 precision medicine  CRISPR-cas9  drug target  biomarker  drug resistance  synergistic lethality   Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment 期刊论文 SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 18, 页码: 11 作者:  Wang, Leiming;  Cheng, Chiang-Min;  Qin, Jun;  Xu, Mafei;  Kao, Chung-Yang 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 Discovery of novel glyceraldehyde-3-phosphate dehydrogenase inhibitor via docking-based virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 96, 页码: 10 作者:  Li, Ting;  Tan, Xiaoqin;  Yang, Ruirui;  Miao, Ying;  Zhang, Min 收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Glyceraldehyde-3-phosphate dehydrogenase  Inhibitor  Virtual screening  Glycolysis  Cancer   Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1 期刊论文 JOURNAL OF BREAST CANCER, 2020, 卷号: 23, 期号: 1, 页码: 20-35 作者:  Deng, Yu;  Guo, Wanjun;  Li, Guancheng;  Li, Shuang;  Li, Hong 收藏  |  浏览/下载：47/0  |  提交时间：2020/07/01 Breast neoplasms  C-terminal binding protein  Protocatechualdehyde