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浏览/检索结果: 共18条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Dynamic modifications of biomacromolecules: mechanism and chemical interventions 期刊论文 SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1459-1471 作者:  Wang, Chu;  Zou, Peng;  Yang, Caiguang;  Liu, Lei;  Cheng, Liang 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 chemical biology  biomacromolecule  dynamic modification  modification analysis  chemical intervention   Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei 收藏  |  浏览/下载：116/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models 期刊论文 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16 作者:  Peng, Xia;  Hou, Pengcong;  Chen, Yi;  Dai, Yang;  Ji, Yinchun 收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 Kinase inhibitor  FGFR  CSF-1R  Tumor microenvironment   Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488 作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Procyanidin C1, a Component of Cinnamon Extracts, Is a Potential Insulin Sensitizer That Targets Adipocytes 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8839-8846 作者:  Sun, Peng;  Li, Kai;  Wang, Ting;  Ji, Jun;  Wang, Yan 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 cinnamon extracts  B-type procyanidin  3T3-L1 adipocytes  insulin sensitivity  glucose uptake   Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5 期刊论文 MOLECULES, 2019, 卷号: 24, 期号: 13, 页码: 14 作者:  Mangoni, Arduino A.;  Vanden Eynde, Jean Jacques;  Jampilek, Josef;  Hadjipavlou-Litina, Dimitra;  Liu, Hong 收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases 期刊论文 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312 作者:  Liu, Man;  Xiao, Cheng-qian;  Sun, Ming-wei;  Tan, Min-jia;  Hu, Li-hong 收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 covalent interaction  IKK inhibitor  JAK inhibitor  natural compound   Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 system 期刊论文 NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 9, 页码: 14 作者:  Qiu, Wenqing;  Xu, Zhijiao;  Zhang, Min;  Zhang, Dandan;  Fan, Hui 收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression via a novel autocrine mechanism 期刊论文 ONCOGENE, 2019, 卷号: 38, 期号: 20, 页码: 3946-3961 作者:  Tang, Bo;  Wu, Jilin;  Zhu, Michael X.;  Sun, Xuemei;  Liu, Jingjing 收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01 The dynamic conformational landscape of the protein methyltransferase SETD8 期刊论文 ELIFE, 2019, 卷号: 8, 页码: 76 作者:  Chen, Shi;  Wiewiora, Rafal P.;  Meng, Fanwang;  Babault, Nicolas;  Ma, Anqi 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01