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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Development of highly potent glucocorticoids for steroid-resistant severe asthma 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 14, 页码: 6932-6937 作者:  He, Yuanzheng;  Shi, Jingjing;  Quang Tam Nguyen;  You, Erli;  Liu, Hongbo 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 steroid resistant asthma  glucocorticoid  high potency  VSG158  VSG159   Design, Synthesis, and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 2950-2973 作者:  Shi, Chenghui;  Zhang, Yinyong;  Wang, Ting;  Lu, Wenchao;  Zhang, Shuhua 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 Magnesium lithospermate B protects the endothelium from inflammation-induced dysfunction through activation of Nrf2 pathway 期刊论文 Acta pharmacologica Sinica, 2019 作者:  Gao, Fei;  Li, Jiao-Meng;  Xi, Cong;  Li, Hui-Hui;  Liu, Ying-Luo 收藏  |  浏览/下载：107/0  |  提交时间：2019/03/13 Nrf2  Pi3k/akt  Pkc  Endothelium  Human Dermal Microvascular Endothelial Cells  Inflammation  Lipopolysaccharide  Magnesium Lithospermate b  Rat Superior Mesenteric Artery Rings   Enhanced Delivery of Imatinib into Vaginal Mucosa via a New Positively Charged Nanocrystal-Loaded in Situ Hydrogel Formulation for Treatment of Cervical Cancer 期刊论文 PHARMACEUTICS, 2019, 卷号: 11, 期号: 1, 页码: 16 作者:  Ci, Li-qian;  Huang, Zhi-gang;  Lv, Feng-mei;  Wang, Jun;  Feng, Ling-lin 收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01 mucoadhesiveness  cervicovaginal tumors  cationic functionalization  imatinib  nanocrystals  in situ hydrogel   Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors 期刊论文 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834 作者:  Niu, Ao;  Wang, Yang;  Yang, Yushe;  Wei, Jianhai;  Ding, Jian 收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01 Non-small cell lung cancer  irreversible inhibitors  EGFR(T79014)( )mutant  anti-tumor  xenograft model  cell proliferation   DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2 期刊论文 CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808 作者:  Kong, Yuanyuan;  Li, Bo;  Chang, Shuaikang;  Gao, Lu;  Xu, Zhijian 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 DCZ0814  multiple myeloma  mTOR  bone marrow microenvironment  apoptosis   magnesiumlithospermatebprotectstheendotheliumfrominflammationinduceddysfunctionthroughactivationofnrf2pathway 期刊论文 actapharmacologicasinica, 2019, 卷号: 40, 期号: 7, 页码: 867 作者:  Gao Fei;  Li Jiaomeng;  Xi Cong;  Li Huihui;  Liu Yingluo 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 magnesium lithospermate B  endothelium  human dermal microvascular endothelial cells  rat superior mesenteric artery rings  lipopolysaccharide  inflammation  Nrf2  PKC  PI3K/Akt