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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
发表日期
2019 [16]
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共16条,第1-10条
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发表日期:2019
专题:上海药物研究所
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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2020/07/01
Current trends in drug metabolism and pharmacokinetics
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 43, 页码: 21732-21738
作者:
Liu, Bin
;
Zhang, Zhijian
;
Hu, Yanyun
;
Lu, Yan
;
Li, Duanzhuo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
type 2 diabetes
gluconeogenesis
hepatic glucose production
ER stress
USP14
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
期刊论文
CELL, 2019, 卷号: 179, 期号: 2, 页码: 561-+
作者:
Gao, Qiang
;
Zhu, Hongwen
;
Dong, Liangqing
;
Shi, Weiwei
;
Chen, Ran
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Metabolic characterization of diabetic retinopathy: An H-1-NMR-based metabolomic approach using human aqueous humor
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 414-421
作者:
Jin, Huiyi
;
Zhu, Bijun
;
Liu, Xia
;
Jin, Jing
;
Zou, Haidong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Metabolomics
NMR analysis
Aqueous humor
Diabetic retinopathy
Metabolite-metabolite correlation
Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 567-577
作者:
Liu, Fang
;
Sun, Zhaolin
;
Hu, Pei
;
Tian, Qiang
;
Xu, Zhou
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Liver injury
Metabolomics
Gut microbiota
LC-MS
Gene sequencing
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 11
作者:
Feng, Zijin
;
Hou, Jinjun
;
Yu, Yang
;
Wu, Wenyong
;
Deng, Yanping
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Uncaria Stem with Hooks
multiple botanical origins
spontaneously hypertensive rats
systolic blood pressure
metabonomics
indole alkaloids
Rapid structure identification of nineteen metabolites of ondansetron in human urine using LC/MSn
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 页码: 7
作者:
Duan, Mingyu
;
Qin, Li
;
Zhong, Dafang
;
Zhang, Peng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
human metabolism
LC
MSn
metabolic pathways
ondansetron
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