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上海药物研究所 [9]
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期刊论文 [29]
学位论文 [1]
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2018 [30]
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Chemistry [2]
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Effects of Alkoxy and Fluorine Atom Substitution of Donor Molecules on the Morphology and Photovoltaic Performance of All Small Molecule Organic Solar Cells
期刊论文
FRONTIERS IN CHEMISTRY, 2018, 卷号: 6
作者:
Qiu, Beibei
;
Chen, Shanshan
;
Xue, Lingwei
;
Sun, Chenkai
;
Li, Xiaojun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/04/09
Benzothiadiazole
Organic Small Molecule Donors
Fluorine Substitution
Alkoxy Side Chain
All smAll Molecule Organic Solar Cells
All-small molecule solar cells based on donor molecule optimization with highly enhanced efficiency and stability
期刊论文
JOURNAL OF MATERIALS CHEMISTRY A, 2018, 卷号: 6, 期号: 32, 页码: 15675-15683
作者:
Guo, Jie
;
Bin, Haijun
;
Wang, Wei
;
Chen, Bingcai
;
Guo, Jing
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  |  
浏览/下载:41/0
  |  
提交时间:2019/04/09
Conformational sensitivity of surface selection rules for quantitative Raman identification of small molecules in biofluids
期刊论文
NANOSCALE, 2018, 卷号: 10, 期号: 29, 页码: 14342-14351
作者:
Li, Lei
;
Wang, Chao
;
Yang, Lina
;
Su, Mengke
;
Yu, Fanfan
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  |  
浏览/下载:16/0
  |  
提交时间:2019/12/10
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:
Liang, Xiaofei
;
Li, Feng
;
Chen, Cheng
;
Jiang, Zongru
;
Wang, Aoli
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  |  
浏览/下载:14/0
  |  
提交时间:2019/12/10
PI3K delta
Kinase inhibitor
Acute myeloid leukemia
Structure-activity relationship
Quinone skeleton as a new class of irreversible inhibitors against Staphylococcus aureus sortase A
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 10, 页码: 1864-1869
作者:
Hou, Xiaochen
;
Wang, Meining
;
Wen, Yi
;
Ni, Tengfeng
;
Guan, Xiangna
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  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Staphylococcus aureus
Anti-virulence
Sortase A
Covalent inhibitor
Quinone skeleton
High-pressure photon ionization time-of-flight mass spectrometry combined with dynamic purge-injection for rapid analysis of volatile metabolites in urine
期刊论文
ANALYTICA CHIMICA ACTA, 2018, 卷号: 1008, 页码: 74-81
作者:
Wang, Yan
;
Hua, Lei
;
Jiang, Jichun
;
Xie, Yuanyuan
;
Hou, Keyong
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  |  
浏览/下载:52/0
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提交时间:2019/06/20
High-pressure Photon Ionization Mass Spectrometry
Dynamic Purge-injection
Urine
Metabolomics
2
5-dimethylpyrrole
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:
Ma, Fei
;
Liu, Jian
;
Zhou, Tingting
;
Lei, Min
;
Chen, Jing
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  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
Thienol2,3-b]pyridine derivatives
Structure-activity relationships (SARs)
Hepatic gluconeogenesis
Type 2 diabetes mellitus (T2DM)
TSPA as a novel ATF6 alpha translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 948-953
作者:
Zhou, Tingting
;
Cheng, Yanhua
;
Yan, Wenzhong
;
Shi, Xiaofan
;
Xu, Xin
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
ATF6 alpha
ER stress
insulin resistance
TSPA
T2DM
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483
作者:
Zhu, Kongkai
;
Jiang, Chengshi
;
Tao, Hongrui
;
Liu, Jingqiu
;
Zhang, Hua
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  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Resynthesis
Virtual screening
Molecular docking
Molecular dynamics simulation
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751
作者:
Xiong, Huan
;
Han, Jie
;
Wang, Jun
;
Lu, Wenchao
;
Wang, Chen
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  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Epigenetics
Histone acetyltransferase
GCN5
High throughput screening
1,8-Acridinedione derivative
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