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CORC

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Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Iron-induced energy supply deficiency and mitochondrial fragmentation in neurons 期刊论文
Journal of neurochemistry, 2018, 卷号: 147, 期号: 6, 页码: 816-830
作者:  Huang, Xiao Tian;  Liu, Xing;  Ye, Chun Yan;  Tao, Ling Xue;  Zhou, Hu
收藏  |  浏览/下载：76/0  |  提交时间：2019/01/08
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:  Gong, Grace Qun;  Wang, Ke;  Dai, Xin-Chuan;  Zhou, Yan;  Basnet, Rajesh
收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08
VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 129, 页码: 177-185
作者:  Zhou, Ling;  Yi, Yuetao;  Yuan, Qing;  Zhang, Jing;  Li, Youjie
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/08
Autophagy-Src Regulates Connexin43-Mediated Gap Junction Intercellular Communication in Irradiated HepG2 Cells 期刊论文
RADIATION RESEARCH, 2018, 卷号: 190, 期号: 5, 页码: 494-503
作者:  Yang, Xiaoyao;  Xu, Shengmin;  Su, Yao;  Chen, Biao;  Yuan, Hang
收藏  |  浏览/下载：31/0  |  提交时间：2019/12/25
Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776
作者:  Liu, Ying-Qiang;  Wang, Ya-Nan;  Lu, Xiao-Yun;  Tong, Lin-Jiang;  Li, Yan
收藏  |  浏览/下载：110/0  |  提交时间：2019/01/08
Structure and Physiological Regulation of AMPK 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 11
作者:  Yan, Yan;  Zhou, X. Edward;  Xu, H. Eric;  Melcher, Karsten
收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways 期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:  Tang, Dan;  Liu, Liu;  Ajiakber, Dildar;  Ye, Jianping;  Xu, Jianjun
收藏  |  浏览/下载：68/0  |  提交时间：2019/01/08

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