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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma 期刊论文 ONCOGENESIS, 2018, 卷号: 7 作者:  Chen, Wei;  Zhang, Hao;  Chen, Zhifeng;  Jiang, Hao;  Liao, Liping 收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08 Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 14, 页码: 6110-6120 作者:  Zhao, Yujun;  Zhou, Bing;  Bai, Longchuan;  Liu, Liu;  Yang, Chao-Yie 收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 页码: 156-175 作者:  Hu, Jianping;  Wang, Yingqing;  Li, Yanlian;  Cao, Danyan;  Xu, Lin 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 BRD4  BI2536  Indoline  WPF binders  c-Myc  PD-L1   Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 31 作者:  Fu, Shibo;  Han, Fangbin;  Zhang, Guangtao;  Ren, Chunyan;  Yi, Zhengzi 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/05 BRD4  bivalent BET inhibitors  gene transcription  TNBC  drug discovery   Inhibition of bromodomain-containing protein 4 ameliorates oxidative stress-mediated apoptosis and cartilage matrix degeneration through activation of NF-E2-related factor 2-heme oxygenase-1 signaling in rat chondrocytes 期刊论文 JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 卷号: 119, 页码: 7719-7728 作者:  An, Qin-de;  Li, Yun-yun;  Zhang, Hong-xing;  Lu, Jun;  Yu, Xiao-dong 收藏  |  浏览/下载：5/0  |  提交时间：2019/11/26 apoptosis  NF-E2-related factor 2-heme oxygenase-1 signaling  oxidative stress  cartilage matrix degeneration  bromodomain-containing protein 4   Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib 期刊论文 CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 11, 页码: 2594-2604 作者:  Liu, Shengwu;  Hai, Josephine;  Wang, Xiaoen;  Quinn, Max M.;  Gao, Peng 收藏  |  浏览/下载：81/0  |  提交时间：2019/04/28 Receptor Tyrosine Kinase  Phase-ii Trial  Bromodomain Inhibition  Combination Therapy  Acquired-resistance  Domain Mutations  Bet Bromodomains  Breast-cancer  Egfr  Mutant   Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression 期刊论文 INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 6 作者:  Tan, Yifan;  Wang, Lei;  Du, Yang;  Liu, Xiuheng;  Chen, Zhiyuan 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05 bromodomain containing protein 4  bromodomain inhibitor  prostate cancer  forkhead box protein O1  p21  c-Myc