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科研机构
山东大学 [29]
复旦大学上海医学院 [22]
西安交通大学 [18]
上海药物研究所 [10]
武汉大学 [10]
昆明医科大学 [7]
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期刊论文 [161]
会议论文 [2]
发表日期
2018 [163]
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发表日期:2018
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Modified citrus pectin inhibited bladder tumor growth through downregulation of galectin-3
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1885-1893
作者:
Fang, Tian
;
Liu, Dan-Dan
;
Ning, He-Ming
;
Sun, Jing-Ya
;
Huang, Xiao-Jing
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/01/08
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/05/15
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2018/12/21
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
Cd2-associated protein contributes to hepatitis c, virus propagation and steatosis by disrupting insulin signaling
期刊论文
Hepatology, 2018, 卷号: 68, 期号: 5, 页码: 1710-1725
作者:
Zhang, Huixia
;
Zhang, Chao
;
Tang, Hong
;
Gao, Shanshan
;
Sun, Fang
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/05/08
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 10, 页码: 3131-3147
作者:
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/06/20
PFAAs
Mitophagy
ER-phagy
Lung toxicity
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:
Zhang, Ning
;
Yu, Zhimei
;
Yang, Xiaohong
;
Zhou, Yan
;
Tang, Qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Proliferation
Anticancer drug
Phosphatidylinositol 3-kinase inhibitor
Apoptosis
Structure-activity relationship
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:
Liang, Xiaofei
;
Li, Feng
;
Chen, Cheng
;
Jiang, Zongru
;
Wang, Aoli
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/10
PI3K delta
Kinase inhibitor
Acute myeloid leukemia
Structure-activity relationship
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 8, 页码: 782-792
作者:
Yu, Dandan
;
Zhang, Yong
;
Chen, Gege
;
Xie, Yongsheng
;
Xu, Zhijian
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
mantle cell lymphoma
pterostilbene
antiproliferative activity
PI3K/Akt/mTOR pathway
synergistic cytotoxicity
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365
期刊论文
ADVANCED SCIENCE, 2018, 卷号: 5, 期号: 7, 页码: -
作者:
Li, Changying
;
Gao, Ming
;
Liu, Sijin
;
Cong, Min
;
Liu, Yun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/06/20
cadmium
long non-coding RNA (lncRNA)
miR-365
MT1DP
Nrf2
oxidative stress
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