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上海药物研究所 [7]
大连理工大学 [2]
高能物理研究所 [2]
海洋研究所 [2]
新疆理化技术研究所 [1]
中南林业科技大学 [1]
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期刊论文 [15]
发表日期
2017 [15]
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Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:
Li, Xiang-Qian
;
Xu, Qi
;
Luo, Jiao
;
Wang, Li-Jun
;
Jiang, Bo
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2017/10/09
Type 2 Diabetes
Ptp1b Inhibition
Selectivity
Competitive
Cellular Activity
A Novel Sarsolenane Diterpene as a PTP1B Inhibitor from Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 8, 页码: 1246-1250
作者:
Liang, Linfu
;
Wang, Jinan
;
Shi, Xiaoxuan
;
Zhu, Yinghua
;
Li, Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Sarcophyton trocheliophrum
sarsolenane
structure elucidation
PTP1B inhibitory activity
binding mode
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:
Zhang, Renshuai
;
Yu, Rilei
;
Xu, Qi
;
Li, Xiangqian
;
Luo, Jiao
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  |  
浏览/下载:22/0
  |  
提交时间:2017/07/10
PTP1B
Bromophenol
Saccharide
Selectivity
Permeability
5-Alkylpyrrole-2-carboxaldehyde derivatives from the Chinese sponge Mycale lissochela and their PTP1B inhibitory activities
期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 6, 页码: 1190-1193
作者:
Xue, Duo-Qing
;
Liu, Hai-Li
;
Chen, Si-Han
;
Mollo, Ernesto
;
Gavagnin, Margherita
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
5-Alkylpyrrole-2-carboxaldehyde
Sponge
Mycale lissochela
PTP1B inhibitor
Marine natural product
Aglaiabbrevins A-D, New Prenylated Bibenzyls from the Leaves of Aglaia abbreviata with Potent PTP1B Inhibitory Activity
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2017, 卷号: 65, 期号: 3, 页码: 295-299
作者:
Sun, Pan
;
Jiang, Chang-Sheng
;
Zhang, Yi
;
Liu, Ai -Hong
;
Liang, Tong -Jun
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Aglaia abbreviata
prenylated bibenzyl
aglaiabbrevin
protein tyrosine phosphatase-1B inhibitor
potential lead compound
Synthesis, crystal structure and ptps inhibition of a zinc(ii) complex with n-(4-hydroxybenzyl)-l-serine
期刊论文
Chinese journal of structural chemistry, 2017, 卷号: 36, 期号: 2, 页码: 316-323
作者:
Li Yan-Hong
;
Lu Li-Ping
;
Zhu Miao-Li
;
Yuan Cai-Xia
;
Feng Si-Si
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/04/23
Zinc(ii) complex
N-(4-hydroxybenzyl)-l-serine
Crystal structure
Inhibitory activity
Ptp1b
Tcptp
Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 4, 页码: 1105-1108
作者:
Dong, Suzhen
;
Lei, Yubing
;
Jia, Shikun
;
Gao, Lixin
;
Li, Jia
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
PTP1B inhibitor
New structure
Oxindole
Polycycle
Spirotetrahydrofurochroman
Anti-diabetic effect of three new norditerpenoid alkaloids in vitro and potential mechanism via PI3K/Akt signaling pathway
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 87, 期号: 3, 页码: 145-152
作者:
Tang, D (Tang, Dan)
;
Chen, QB (Chen, Qi-Bin)
;
Xin, XL (Xin, Xue-Lei)
;
Aisa, HA (Aisa, Haji-Akber)
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/04/05
Diabetes
Norditerpenoid alkaloids
Anti-diabetic activity
Glucose metabolism
Protein tyrosine phosphatase 1B
PI3K/Akt signaling pathway
Synthesis, Crystal Structure and PTPs Inhibition of a Zinc(II) Complex with N-(4-hydroxybenzyl)-L-serine
期刊论文
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY结构化学, 2017, 卷号: 36, 期号: 2, 页码: 316-323
作者:
Zhu, ML
;
Yuan, CX
;
Feng, SS
;
Gao ZQ(高增强)
;
Gao, ZQ
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/08/27
zinc(II) complex
N-(4-hydroxybenzyl)-L-serine
crystal structure
inhibitory activity
PTP1B
TCPTP
Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes
期刊论文
LIFE SCIENCES, 2017, 卷号: 169, 页码: 52-64
作者:
Sun, Wenlong
;
Zhang, Bowei
;
Zheng, Haizhou
;
Zhuang, Chunlin
;
Li, Xia
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Trivaric acid
Protein tyrosine phosphatase 1b
Insulin sensitivity
Insulin signalling pathway
Diabetes
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