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科研机构
武汉大学 [3]
北京大学 [2]
西安交通大学 [2]
成都生物研究所 [1]
上海药物研究所 [1]
水生生物研究所 [1]
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内容类型
期刊论文 [15]
发表日期
2017 [15]
学科主题
Pharmacolo... [1]
Toxicology [1]
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DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway
期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8
作者:
Sun, Xi
;
Li, Bo
;
Xie, Bingqian
;
Xu, Zhijian
;
Chang, Gaomei
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
Intestinal immune responses of Jian carp against Aeromonas hydrophila depressed by choline deficiency: Varied change patterns of mRNA levels of cytokines, tight junction proteins and related signaling molecules among three intestinal segments
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 65, 期号: 1, 页码: 34-41
作者:
Wu, Pei
;
Liu, Yang
;
Jiang, Wei-Dan
;
Jiang, Jun
;
Zhang, Yong-An
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/09/02
Choline
Intestinal inflammation
Jian carp
NF-kappa B
Tight junction protein
Hepatocyte growth factor inhibits tubular epithelial-myofibroblast transdifferentiation by suppression of angiotensin II via the JAK2/STAT3 signaling pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 15, 期号: 5
作者:
Zhang, Chen
;
Cui, Ming-Ji
;
Gu, Chun-Mei
;
Chen, Yan
;
Dou, Hai-Chuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
hepatocyte growth factor
angiotensin II
tubular epithelial-myofibroblast transdifferentiation
Janus kinase 2/signal transducer and activator of transcription 3 signaling
Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials
期刊论文
Human Immunology, 2017, 卷号: 78, 期号: 2, 页码: 120-128
作者:
Deng, Yaxiong
;
Wang, Zijun
;
Chang, Christopher
;
Lu, Liwei
;
Sing Lau, Chak
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/03
IL
interleukin
TGF-β
transforming growth factor β
SLE
systemic lupus erythematosus
MS
multiple sclerosis
IBD
inflammatory bowel diseases
RA
rheumatoid arthritis
mAb
monoclonal antibody
IFN-γ
interferon gamma
TNF-α
tumor necrosis factor alpha
Tregs
regulatory T cells
EAE
experimental autoimmune encephalitis
ETS
E26-transformation-specific
STAT
activators of transcription
JAK
Janus kinase
NO
nitric oxide
LPS
lipopolysaccharide
ILC2
type II innate lymphoid cells
ROI
reactive oxygen intermediates
TPO
thrombopoietin
EPO
hemopoietin
SCF
stem cell factor
ASM
airway smooth muscle
SLEDAI
SLE disease activity index
dsDNA
double-stranded DNA
CNS
central nervous system
MOG
myelin oligodendrocyte glycoprotein
CCL20
chemokine ligand 20
RR-MS
relapsing-remitting multiple sclerosis
CD
Crohn’s disease
UC
ulcerative colitis
CIA
collagen-induced arthritis
Th9
IL-9
Differentiation
Autoimmune disease
Treatments
Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2017
Kong, Yuan
;
Wu, Yi-Lin
;
Song, Yang
;
Shi, Min-Min
;
Cao, Xie-Na
;
Zhao, Hong-Yan
;
Qin, Ya-Zhen
;
Lai, Yue-Yun
;
Jiang, Hao
;
Jiang, Qian
;
Huang, Xiao-Jun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
Acute lymphoblastic leukemia
Ph-chromosome
Leukemia-propagating cells
Nilotinib
Ruxolitinib
ACUTE MYELOID-LEUKEMIA
Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 75-83
作者:
Wang, Yazhou
;
Huang, Wei
;
Xin, Minhang
;
Chen, Pan
;
Gui, Li
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
4-(2-Furanyl)pyrimidin-2-amine
JAK2 inhibitor
4,5,6,7-Tetrahydro-furo[3,2-c]pyridine
Kinase selectivity
Anti-Double-Stranded DNA IgG Participates in Renal Fibrosis through Suppressing the Suppressor of Cytokine Signaling 1 Signals
期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8
作者:
Wang, Ping
;
Yang, Jie
;
Tong, Fang
;
Duan, Zhaoyang
;
Liu, Xingyin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/11/26
suppressor of cytokine signaling 1
peptide
lupus nephritis
signal transducer and activator of transcription 1
anti-double-stranded DNA IgG
Janus kinase 2
renal fibrosis
Tofacitinib ameliorates atherosclerosis and reduces foam cell formation in apoE deficient mice
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017
Wang, Zaicun
;
Wang, Shumei
;
Wang, Zunzhe
;
Yun, Tiantian
;
Wang, Chenchen
;
Wang, Huating
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
Tofacitinib
Atherosclerosis
Macrophage
Inflammation
Foam cell formation
PATHWAY-DEPENDENT MANNER
ABCA1 EXPRESSION
APOLIPOPROTEIN-E
JAK INHIBITOR
DIFFERENTIATION
MACROPHAGES
SUPPRESSORS
ACTIVATION
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon alpha/beta by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017, 卷号: 336, 页码: 31-39
作者:
Wonganan, O
;
He, YJ
;
Shen, XF
;
Wongkrajang, K
;
Suksamrarn, A
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2018/08/28
Kaempferol Glucopyranoside
Saussurea Stella
Interferon
Jak/stat
Socs3
Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice.
期刊论文
BMC Complement Altern Med, 2017, 卷号: Vol.17 No.1, 页码: 12
作者:
Li J
;
Wei Y
;
Li X
;
Zhu D
;
Nie B
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/27
Collagen-induced arthritis (CIA)
Janus-activated kinase-signal transducer and activator of transcription (JAK/STAT)
Lymphocyte
Nuclear factor κB (NF-κB)
Pro-inflammatory cytokine
Xian-fang-huo-ming-Yin (XFHM)
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