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科研机构
西安交通大学 [5]
南华大学 [3]
兰州大学 [3]
上海药物研究所 [3]
山东大学 [3]
中南大学 [3]
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内容类型
期刊论文 [35]
发表日期
2016 [35]
学科主题
Pharmacolo... [1]
cell biolo... [1]
oncology; ... [1]
医学心理学 [1]
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Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway
期刊论文
PHYTOMEDICINE, 2016, 卷号: 23, 期号: 14, 页码: 1806-1813
作者:
Zhang, Liu
;
Zhang, Hui
;
Li, Xueyan
;
Jia, Bingjie
;
Yang, Yuyu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Miltirone
Nrf2
HO-1
Endothelial dysfunction
Oxidative stress
Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 8
作者:
Liu, Ming
;
Chen, Fangling
;
Yu, Rilei
;
Zhang, Weiyi
;
Han, Mei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/08/19
3-O-angeloyl-20-O-acetyl ingenol
PEP008
20-O-acetyl-ingenol-3-angelate
ingenol mebutat
apoptosis
chronic myeloid leukemia
Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 8
作者:
Liu, Ming
;
Chen, Fangling
;
Yu, Rilei
;
Zhang, Weiyi
;
Han, Mei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2018/12/07
3-O-angeloyl-20-O-acetyl ingenol
PEP008
20-O-acetyl-ingenol-3-angelate
ingenol mebutat
apoptosis
chronic myeloid leukemia
Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2)
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 11, 页码: 2600-2604
作者:
Li, Lei
;
Liu, Feifei
;
Jin, Nan
;
Tang, Shuai
;
Chen, Zhuxi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
ERK1/2 kinase inhibitor
Indazole amide
Structure based drug design
The role of protein kinase C alpha translocation in radiation-induced bystander effect
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 无, 页码: 1-9
作者:
Fang, Zihui
;
Xu, An
;
Wu, Lijun
;
Hei, Tom K.
;
Hong, Mei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2017/11/10
Fluid shear stress suppresses TNF-alpha-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways
期刊论文
EXPERIMENTAL CELL RESEARCH, 2016, 卷号: 343, 期号: 2, 页码: 208-217
作者:
Geng, B
;
Zhang, B
;
Wang, J
;
Jiang, J
;
Tan, XY
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/01/10
Fluid shear stress
Extracellular signal-regulated kinase 5
Forkhead box O 3a
FasL
Bim
Osteoblasts
Discovery of 1,3-Diaryl-pyridones as Potent VEGFR-2 Inhibitors: Design, Synthesis, and Biological Evaluation
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 87, 期号: 5, 页码: 694-703
作者:
Yan, Wei
;
Huang, Zhaoru
;
Wang, Zhengyu
;
Cao, Sufen
;
Tong, Linjiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
1
3-Diaryl-pyridone
angiogenesis
anticancer agent
Chan-Lam coupling
VEGFR-2 inhibitors
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways
期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 页码: 3009-3016
作者:
Jing, Huiling
;
Sun, Wenyan
;
Fan, Jinghua
;
Zhang, Yanmin
;
Yang, Jiao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
apoptosis
reactive oxygen species
Akt
HaCaT cells
extracellular signal-regulated kinase
shikonin
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling
期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:
Liu, Jianxin
;
Tang, Jinshan
;
Zuo, Yihan
;
Yu, Yang
;
Luo, Pei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/03
NO
nitric oxide
PGE2
prostaglandin E2
NSAIDs
non-steroidal anti-inflammatory drugs
qRT-PCR
quantitative real-time polymerase chain reaction
LPS
lipopolysaccharide
IFN-γ
interferon γ
G-CSF
granulocyte colony stimulating factor
TNF-α
tumor necrosis factor-α
IL-1β
interleukin-1β
IL-6
interleukin-6
MCP-1
monocyte chemoattractant protein-1
NF-κB
Nuclear factor-κB
IκB
inhibitory protein
IKK
IκB kinase
RPS3
ribosomal protein S3
iNOS
inducible nitric oxide synthase
COX-2
cyclooxygenase-2
PGESs
prostaglandin E2 synthases
mPGES-1
microsomal prostaglandin synthetase-1
mPGES-2
microsomal prostaglandin E synthase-2
cPGES
cytosolic prostaglandin E synthase
MAPK
mitogen-activated protein kinases
ERK
extracellular signal-regulated kinase
JNK
c- Jun N-terminal kinase
PGI2
prostacyclin I2
PGD2
prostaglandin D2
PGF2α
prostaglandin F2α
TXA2
thromboxane A2
Stauntoside B (PubChem CID: 101010462)
Stauntoside B
Cynanchi stauntonii
Lipopolysaccharide
Anti-inflammatory activity
NF-κB
MAPK
Roles of 1,25(OH)(2)D-3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4(+) T Cells and the PKC delta/ERK Signaling Pathway
期刊论文
Cellular Physiology and Biochemistry, 2016, 卷号: 40, 期号: 3-4, 页码: 743-756
作者:
He, Xiao-Jie*
;
Ding, Yan
;
Xiang, Wei
;
Dang, Xi-Qiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
Systemic lupus erythematosus
Rheumatoid arthritis
1,25(OH)(2)D-3
Vitamin D receptor
Protein kinase C delta
Extracellular signal-regulated kinase
CD4(+) T cells
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