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Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance 期刊论文
Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:38/0  |  提交时间:2019/05/09
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to gamma-secretase cleavage and the A beta 42/A beta 40 ratio 期刊论文
CELL DISCOVERY, 2016, 卷号: 2
作者:  Xu, Ting-Hai;  Yan, Yan;  Kang, Yanyong;  Jiang, Yi;  Melcher, Karsten
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Selenomethionine reduces the deposition of beta-amyloid plaques by modulating beta-secretase and enhancing selenoenzymatic activity in a mouse model of alzheimer's disease 期刊论文
Metallomics, 2016, 卷号: 8, 期号: 8, 页码: 782-789
作者:  Zhang, Zhong-Hao;  Chen, Chen;  Wu, Qiu-Yan;  Zheng, Rui;  Liu, Qiong
收藏  |  浏览/下载:45/0  |  提交时间:2019/05/09
A Novel Multifunctional Compound Camellikaempferoside B Decreases A beta Production, Interferes with A beta Aggregation, and Prohibits A beta-Mediated Neurotoxicity and Neuroinflammation 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2016, 卷号: 7, 期号: 4, 页码: 505-518
作者:  Yang, Shigao;  Liu, Wen;  Lu, Shuai;  Tian, Yong-zhen;  Wang, Wei-yun
收藏  |  浏览/下载:16/0  |  提交时间:2016/07/15
Sequential combination therapy of ovarian cancer with cisplatin and gamma-secretase inhibitor MK-0752 期刊论文
2016, 卷号: 140, 期号: [db:dc_citation_issue], 页码: 537
作者:  Chen, XiuXiu[1];  Gong, LiHua[1];  Ou, RongYing[1];  Zheng, ZhenZhen[1];  Chen, JinYan[1]
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/03
Dual Signal Amplification Electrochemical Biosensor for Monitoring the Activity and Inhibition of the Alzheimer's Related Protease β-Secretase 期刊论文
Analytical Chemistry, 2016, 卷号: 88, 期号: 21, 页码: 10559-10565
作者:  Qu, Fengli;  Yang, Minghui*;  Rasooly, Avraharn*
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Notch signaling in lung diseases: focus on Notch1 and Notch3. 期刊论文
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2016, 卷号: 10, 期号: 5, 页码: 468-484
作者:  Zong, Dandan;  Ouyang, Ruoyun;  Li, Jinhua;  Chen, Yan;  Chen, Ping*
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Familial acne inversa, a genetic disease of gamma-secretase inversa impact keratinocyte proliferation and differentiation through Notch and PI3K-AKT signaling pathways 期刊论文
2016, 卷号: 25, 期号: ,SI, 页码: 2-2
作者:  Wang, B.
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/04
Familial acne inversa, a genetic disease of gamma-secretase inversa impact keratinocyte proliferation and differentiation through Notch and PI3K-AKT signaling pathways 会议论文
EXPERIMENTAL DERMATOLOGY, 2016-02-01
作者:  Wang, B.
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/04


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