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	Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride
	Zhu, FQ (Zhu, Fuqiang); Aisa, HA (Aisa, Haji A.); Zhang, J (Zhang, Jian); Hu, TW (Hu, Tianwen); Sun, CL (Sun, Changliang); He, Y (He, Yang); Xie, YC (Xie, Yuanchao); Shen, JS (Shen, Jingshan)
刊名	ORGANIC PROCESS RESEARCH & DEVELOPMENT
	2018
卷号	22期号:1页码:91-96
ISSN号	1083-6160
DOI	10.1021/acs.oprd.7b00350
英文摘要	An efficient route for the preparation of 4-methylenepiperidine hydrochloride 1 was designed, and then a process feasible for large-scale production was developed with a total yield of 83.5% at a purity of 99.9%.
WOS记录号	WOS:000423252100009
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/5497]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室
通讯作者	Aisa, HA (Aisa, Haji A.)
作者单位	1.Chinese Acad Sci, Key Lab Plant Resources & Chem Arid Reg, Xinjiang Tech Inst Phys & Chem, South Beijing Rd 40-1, Urumqi 830011, Xinjiang, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 4.Topharman Shanghai Co Ltd, Bldg 1,388 Jialilue Rd,Zhangjiang Hitech Pk, Shanghai 201209, Peoples R China
推荐引用方式 GB/T 7714	Zhu, FQ ,Aisa, HA ,Zhang, J ,et al. Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride[J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT,2018,22(1):91-96.
APA	Zhu, FQ .,Aisa, HA .,Zhang, J .,Hu, TW .,Sun, CL .,...&Shen, JS .(2018).Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride.ORGANIC PROCESS RESEARCH & DEVELOPMENT,22(1),91-96.
MLA	Zhu, FQ ,et al."Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride".ORGANIC PROCESS RESEARCH & DEVELOPMENT 22.1(2018):91-96.

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