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A deep learning method for repurposing antiviral drugs against new viruses via multi-view nonnegative matrix factorization and its application to SARS-CoV-2
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-16
作者:
Su, XR (Su, Xiaorui) [1]
;
Hu, L (Hu, Lun) [1]
;
You, ZH (You, Zhuhong) [2]
;
Hu, PW (Hu, Pengwei) [1]
;
Wang, L (Wang, Lei) [3]
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/05/06
SARS-CoV-2
drugrepositioning
constrained multi-view nonnegative matrix factorization
deeplearning
graphconvolutionalnetwork
HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
Degradation characteristics of electron and proton irradiated InGaAsP/InGaAs dual junction solar cell
期刊论文
SOLAR ENERGY MATERIALS AND SOLAR CELLS, 2020, 卷号: 206, 期号: 3, 页码: 1-7
作者:
Zhao, XF (Zhao, X. F.)[ 1 ]
;
Aierken, A (Aierken, A.)[ 1,2 ]
;
Heini, M (Heini, M.)[ 1,3 ]
;
Tan, M (Tan, M.)[ 4 ]
;
Wu, YY (Wu, Y. Y.)[ 4 ]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/04/21
InGaAsP/InGaAs solar cell
Electron and proton irradiation
Degradation
Equivalent displacement damage dose model
1 meV electron irradiation and post-annealing effects of GaInAsN diluted nitride alloy with 1 eV bandgap energy
期刊论文
THIN SOLID FILMS, 2020, 卷号: 709, 期号: 9, 页码: 1-5
作者:
Sailai, M (Sailai, Momin)[ 1 ]
;
Lei, QQ (Lei, Qi Qi)[ 1,2 ]
;
Aierken, A (Aierken, Abuduwayiti)[ 1,3 ]
;
Heini, M (Heini, Maliya)[ 1,4 ]
;
Zhao, XF (Zhao, Xiao Fan)[ 1 ]
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/10/23
Gallium indium arsenide nitride alloy
Electron irradiation
Photoluminescence
Thermal annealing
Arrhenius plot
Protein-Protein Interactions Prediction via Multimodal Deep Polynomial Network and Regularized Extreme Learning Machine
期刊论文
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2019, 卷号: 23, 期号: 3, 页码: 1290-1303
作者:
Lei, HJ (Lei, Haijun)[ 1 ]
;
Wen, YT (Wen, Yuting)[ 1 ]
;
You, ZH (You, Zhuhong)[ 2 ]
;
Elazab, A (Elazab, Ahmed)[ 3 ]
;
Tan, EL (Tan, Ee-Leng)[ 4 ]
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/06/28
Protein-protein interactions
prediction
multimodal deep polynomial network
regularization extreme learning machine
Pro-fibrotic effects of IL-17A and elevated IL-17RA in IPF and RA-ILD support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease
期刊论文
American journal of physiology. Lung cellular and molecular physiology, 2019
作者:
Zhang Jie[1]
;
Wang Dan[2]
;
Wang Lei[3]
;
Wang Shaohua[4]
;
Roden Anja C[5]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/22
Human Lung Fibroblast
IL-17A IL-17RA
IPF RA-ILD
JAK Inhibitors STAT3
NF-кB Rheumatoid Arthritis
Therapeutic effects on rheumatoid arthritis treated with shu-deep needling and bloodletting techniques
期刊论文
Zhongguo zhen jiu, 2019, 卷号: 39, 页码: 49-53
作者:
Lu Yu-Sun[1]
;
Zong Lei[2]
;
Hou Wen-Guang[3]
;
Zeng Liang[4]
;
Zhao Ran[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/22
HAQ score
VAS
bloodletting technique
rheumatoid arthritis
shu-deep needling technique
Carotid artery plaque intervention with Tongxinluo capsule (CAPITAL): A multicenter randomized double-blind parallel-group placebo-controlled study
期刊论文
Scientific reports, 2019, 卷号: 9, 页码: 4545
作者:
Zhang Mei[1]
;
Liu Yan[2]
;
Xu Mingjun[3]
;
Zhang Lei[4]
;
Liu Xiaoling[6]
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/04/22
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