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中国医学科学院 北... [13]
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期刊论文 [30]
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Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
The correlation between the abundance of EGFR T790M mutation and osimertinib response in advanced non-small cell lung cancer
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Pan, Guoqiang
;
Chen, Kaiyan
;
Yu, Xiaoqing
;
Sheng, Jiamin
;
Fan, Yun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/01
Non-small cell lung cancer (NSCLC)
T790M abundance
droplet digital PCR (ddPCR)
next generation sequencing (NGS)
osimertinib
Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261
作者:
Zhao, Pengfei
;
Zhang, Jiaxin
;
Wu, Aihua
;
Zhang, Meng
;
Zhao, Yuge
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2021/05/24
Brain targeting delivery
Tumor-associated macrophage
Osimertinib resistance
Brain metastasis
Innate immunity
Combination therapy
Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth
期刊论文
CANCER LETTERS, 2020, 卷号: 493
作者:
Hu, Lulu
;
Shen, Dachuan
;
Liang, Dapeng
;
Shi, Ji
;
Song, Chunyan
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  |  
浏览/下载:58/0
  |  
提交时间:2020/11/30
Glioblastoma (GBM)
EGFR
EGFRvIII
TRIP13
Osimertinib
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Chen, Cheng
;
Cheng, Chuan-dong
;
Wu, Hong
;
Wang, Zuo-wei
;
Wang, Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
glioblastoma
osimertinib
temozolamide
MAPK-signaling pathway
MNK
eukaryotic translation initiation factor 4E
[Mechanism of MALAT1 induced osimertinib resistance in HCC827 lung cancer cells].
期刊论文
Zhonghua zhong liu za zhi [Chinese journal of oncology], 2019, 卷号: 41, 期号: 4
作者:
Kang X H
;
Gao Y Y
;
Wang Y
;
Cui Y H
;
Zhao K L
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Epidermal growth factor receptor
Lung neoplasms
Metastasis associated in lung adenocarcinoma transcript
Osimertinib
Cost-Effectiveness of Osimertinib in Treating Newly Diagnosed, Advanced EGFR-Mutation-Positive Non-Small Cell Lung Cancer
期刊论文
ONCOLOGIST, 2019, 卷号: 24, 期号: 3
作者:
Wu, Bin
;
Gu, Xiaohua
;
Zhang, Qiang
;
Xie, Feng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Osimertinib
Non-small cell lung cancer
EGFR mutation
Cost-effectiveness
First-generation EGFR-TKI
Degradation of MCL-1 by bufalin reverses acquired resistance to osimertinib in EGFR-mutant lung cancer
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 379
作者:
Cao, Fei
;
Gong, Ya-Bin
;
Kang, Xiao-Hong
;
Lu, Zhi-Hong
;
Wang, Ying
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/05
Non-small cell lung cancer (NSCLC)
Osimertinib
Bufalin
MCL-1
EGFR
Ku70
Osimertinib (AZD9291) increases radio-sensitivity in EGFR T790M non-small cell lung cancer
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 1, 页码: 77-86
作者:
Wang, Nannan
;
Wang, Linlin
;
Meng, Xiangjiao
;
Wang, Jia
;
Zhu, Lifang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/11
non-small cell lung cancer
epidermal growth factor receptor
T790M
mutation
osimertinib
ionizing radiation
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