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CORC

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Preclinical characterization of LOXO-338, a novel, oral and selective BCL2 inhibitor. 期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 13, 页码: 1
作者:  Brandhuber, Barbara;  Ku, Karin;  Lallena, Maria J.;  Baquero, Carmen;  Choy, Regina
收藏  |  浏览/下载：9/0  |  提交时间：2021/11/04
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li
收藏  |  浏览/下载：74/0  |  提交时间：2021/06/11
YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer 期刊论文
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:  Wang, Lei;  Wang, Quanren;  Xu, Piaopiao;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24
Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992
作者:  Song, Bichao;  Xie, Peipei;  Li, Yingzi;  Hao, Jiping;  Wang, Lu
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 8
作者:  Chen, Lu;  Quan, Haitian;  Xu, Zhongliang;  Wang, Hao;  Xia, Yuanzhi
收藏  |  浏览/下载：17/0  |  提交时间：2020/12/24
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
AG-221  IDH2  leukemia  R140Q  R172K  
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models 期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:  Long, Fei;  He, Ye;  Fu, Haoyu;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response 期刊论文
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353
作者:  Liu, Peng;  Chen, Xiangling;  Zhu, Jianming;  Li, Bo;  Chen, Zhaoqiang
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01

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