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上海药物研究所 [3]
上海中医药大学 [2]
中国医学科学院 北京... [2]
兰州化学物理研究所 [2]
厦门大学 [1]
山东大学 [1]
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期刊论文 [16]
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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration
期刊论文
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
作者:
Ya-Nan Geng
;
Ming Zhao
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/30
Gypenoside-14 (GP-14)
Neuronal Damage
Hypoxia
Transcriptome Sequencing
Neuroprotection
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
作者:
Ya-Nan Geng
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Feng Yan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/11/30
Gypenoside
Neuroinflammation
Blood brain barrier
High altitude cerebral edema
NF-κB signaling pathway
Metabolic mechanisms of Fuzheng-Huayu formula against liver fibrosis in rats
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 238
作者:
Hu, Xue-Qing
;
Song, Ya-Nan
;
Wu, Rong
;
Cai, Fei-Fei
;
Zhang, Yongyu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Fuzheng-Huayu formula
Gypenoside
Cordyceps sinensis mycelia
Amygdalin
Metabolite
Liver fibrosis
Gypenoside IX Suppresses p38 MAPK/Akt/NF kappa B Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators
期刊论文
INFLAMMATION, 2017, 卷号: 40, 期号: 6
作者:
Wang, Xiaoshuang
;
Yang, Liu
;
Yang, Li
;
Xing, Faping
;
Yang, Hua
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
gypenoside IX
astrocyte
neuroinflammation
inflammatory mediator
NF kappa B
Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators
期刊论文
Inflammation, 2017, 卷号: 40, 页码: 2137-2150
作者:
Wang Xiaoshuang[1]
;
Yang Liu[2]
;
Yang Li[3]
;
Xing Faping[4]
;
Yang Hua[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/26
NFκB
astrocyte
gypenoside IX
inflammatory mediator
neuroinflammation
Gypenoside inhibits interleukin-1-induced inflammatory response in human osteoarthritis chondrocytes
期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017, 卷号: 31, 期号: 9
作者:
Wan Zhi-Hong[1]
;
Zhao Qing[2]
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
gypenoside (GP) (OA)
inflammation
NF-kappa B signaling pathway
osteoarthritis
Gypenoside XVII Prevents Atherosclerosis by Attenuating Endothelial Apoptosis and Oxidative Stress: Insight into the ER-Mediated PI3K/Akt Pathway
期刊论文
2017, 卷号: 18, 期号: 2
作者:
Yang, Ke
;
Zhang, Haijing
;
Luo, Yun
;
Zhang, Jingyi
;
Wang, Min
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
gypenoside XVII
estrogen receptors
atherosclerosis
oxidative damage
apoptosis
Gypenoside L, Isolated from Gynostemma pentaphyllum, Induces Cytoplasmic Vacuolation Death in Hepatocellular Carcinoma Cells through Reactive-Oxygen-Species-Mediated Unfolded Protein Response
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016, 卷号: 64, 期号: 8
作者:
Li, Yan
;
Fan, Xinmin
;
Fan, Long
;
Xu, Hong
;
Kang, Qiangrong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
gypenoside L
vacuolation death
ROS
unfolded protein response
calcium release
A new dammarane-type saponin from Gynostemma pentaphyllum induces apoptosis in A549 human lung carcinoma cells
期刊论文
2016, 卷号: 26, 期号: 7, 页码: 1754-1759
作者:
Xing, Shao-Fang
;
Jang, Moonhee
;
Wang, Yu-Rong
;
Piao, Xiang-Lan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Gynostemma pentaphyllum
Cytotoxicity
A549 human lung cancer cells
Gypenoside
Apoptosis
Simultaneous determination of gypenoside LVI, gypenoside XLVI, 2 alpha-OH-protopanaxadiol and their two metabolites in rat plasma by LC MS/MS and its application to pharmacokinetic studies
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 1005, 页码: 9-16
作者:
Zhang, Lihua
;
Lin, Yunfei
;
Guan, Huashi
;
Hu, Lihong
;
Pan, Guoyu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Gypenoside
2 alpha-OH-Protopanaxadiol
Gynostemma pentaphyllum
Validation
Pharmacokinetic
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