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浏览/检索结果:
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A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis
期刊论文
Cell, 2019, 卷号: 176, 页码: 1113-1127.e16
作者:
Yin Chengqian[1]
;
Zhu Bo[2]
;
Zhang Ting[3]
;
Liu Tongzheng[4]
;
Chen Shuyang[5]
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/04/22
NRAS
RAS
STK19
cancer
drug screening
kinase inhibitor
melanoma
melanomagenesis
targeted cancer therapy
Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism
期刊论文
Neuropeptides, 2019, 卷号: 74, 页码: 34-43
作者:
Chen Dequan[1]
;
Cao Shicheng[2]
;
Chang Bo[3]
;
Ma Tie[4]
;
Gao Haining[5]
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/04/22
Chronic inflammation
Diet and exercise
Hypogonadotropic hypogonadism
Nesfatin-1
Obesity
Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads
期刊论文
Nature communications, 2019, 卷号: 10, 页码: 877
作者:
Chen Shuyang[1]
;
Han Changpeng[2]
;
Miao Xiao[3]
;
Li Xin[4]
;
Yin Chengqian[5]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/04/22
Saturation and stability in internal resonance of a rotating blade under thermal gradient
期刊论文
JOURNAL OF SOUND AND VIBRATION, 2019, 卷号: 440, 页码: 34-50
作者:
Zhang, Bo[1]
;
Zhang, Yan-Lei[2]
;
Yang, Xiao-Dong[3]
;
Chen, Li-Qun[4]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/22
Rotating pre-deformed blade
Thermal gradient
2:1 Internal resonance
Saturation
Jumping
Colored distributions
Stability regions
A single factor induces neuronal differentiation to suppress glioma cell growth
期刊论文
CNS neuroscience & therapeutics, 2019, 卷号: 25, 页码: 486-495
作者:
Fu Ji-Qiang[1]
;
Chen Zhen[2]
;
Hu Yong-Jia[3]
;
Fan Zhao-Huan[4]
;
Guo Zhen-Xing[5]
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/04/22
SOX11
U87
ZIC1
cell growth
glioma
neuronal differentiation
reprogramming
transcription factor
Results from the China 2018 Report Card on physical activity for children and youth
期刊论文
Journal of exercise science and fitness, 2019, 卷号: 17, 页码: 3-7
作者:
Liu Yang[1]
;
Tang Yan[2]
;
Cao Zhen-Bo[3]
;
Zhuang Jie[4]
;
Zhu Zheng[5]
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/04/22
The visualization of rub-impact characteristics of drill string on casing
期刊论文
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING, 2019, 卷号: 174, 页码: 1321-1331
作者:
Chen, Laoyin[1]
;
Di, Qinfeng[2]
;
Lou, Erbiao[3]
;
Zhou, Bo[4]
;
Zhang, He[5]
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/04/22
Rub-impact characteristics
3D visualization method
Casing wear
Drill string
Finite element model
Molecularly engineered metal-based bioactive soft materials - Neuroactive magnesium ion/polymer hybrids
期刊论文
ACTA BIOMATERIALIA, 2019, 卷号: 85, 页码: 310-319
作者:
Sun, Lijie[1]
;
Wang, Min[2]
;
Chen, Shuo[3]
;
Sun, Binbin[4]
;
Guo, Yifan[5]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/04/22
Metal ion
Polymer hybrid
Poly(glycerol-sebacate)
Controlled release
Schwann cells
Soft biomaterials
Qualitative and quantitative determination of Atractylodes rhizome using ultra-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry with data-dependent processing
期刊论文
Biomedical chromatography : BMC, 2019, 卷号: 33, 页码: e4443
作者:
Zhang Yihan[1]
;
Bo Cui[2]
;
Fan Yanhao[3]
;
An Rui[4]
;
Chen Long[5]
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/04/22
Atractylodes rhizome
LTQ-Orbitrap MS
chemical component
data-dependent processing
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