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中国医学科学院 北京... [9]
上海药物研究所 [4]
北京大学 [2]
江苏大学 [1]
四川大学 [1]
山东大学 [1]
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期刊论文 [22]
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A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:
Bu, Wenxuan
;
Li, Bo
;
Feng, Lijin
;
Feng, Qilin
;
Hu, Ke
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/16
Multiple myeloma
DCZ0858
mTOR
bone marrow microenvironment
cell proliferation
cell apoptosis
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 8
作者:
Zhang, Silin
;
Xiong, Yunhe
;
Zhang, Yixian
;
Zhao, Hongmei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
acute myeloid leukemia (AML)
bone marrow (BM) microenvironment
dihydroevocarpine
mTOR complex 1 (mTORC1)
mTOR complex 2 (mTORC2)
Multilevel defects in the hematopoietic niche in essential thrombocythemia
期刊论文
2019
作者:
Sun Ting
;
Ju Mankai
;
Dai Xinyue
;
Dong Huan
;
Gu Wenjing
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/01/03
Bone Marrow Microenvironment
Chronic Myeloproliferative Disorders
Hematopoiesis
One cell one niche: hematopoietic microenvironments constructed by bone marrow stromal cells with fibroblastic and histiocytic features
期刊论文
2019, 卷号: 43, 期号: 2-3, 页码: 117-125
作者:
Ru Yong-Xin
;
Dong Shu-Xu
;
Zhao Shi-Xuan
;
Li Yuan
;
Liang Hao-Yue
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Hematopoietic microenvironment
bone marrow stromal cell
maturing hematopoietic cells
niche
CXCL8 derived from mesenchymal stromal cells supports survival and proliferation of acute myeloid leukemia cells through the PI3K/AKT pathway
期刊论文
2019, 卷号: 33, 期号: 4, 页码: 4755-4764
作者:
Cheng, Jingying
;
Li, Ying
;
Liu, Shiqi
;
Jiang, Yajing
;
Ma, Jiao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
cytokines
cancer
bone marrow microenvironment
crosstalk
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:
Kong, Yuanyuan
;
Li, Bo
;
Chang, Shuaikang
;
Gao, Lu
;
Xu, Zhijian
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
DCZ0814
multiple myeloma
mTOR
bone marrow microenvironment
apoptosis
The role of mmu-miR-155-5p-NF-B signaling in the education of bone marrow-derived mesenchymal stem cells by gastric cancer cells
期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 3, 页码: 856-868
作者:
Wang, Mei[1]
;
Yang, Fang[2]
;
Qiu, Rong[3]
;
Zhu, Mengchu[4]
;
Zhang, Huiling[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
Bone marrow-derived mesenchymal stem cells
Gastric cancer
miR-155-5p
NF-B p65
tumor microenvironment
Niche TWIST1 is critical for maintaining normal hematopoiesis and impeding leukemia progression
期刊论文
2018, 卷号: 103, 期号: 12, 页码: 1969-1979
作者:
Liu, Xiaoyan
;
Ma, Yanping
;
Li, Rongrong
;
Guo, Dan
;
Wang, Nan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Acute Myeloid Leukemia
Bone Marrow Microenvironment
Hematopoietic Stem Cell
Leukemic Stem Cell
JAK2V617F-bearing vascular niche enhances malignant hematopoietic regeneration following radiation injury
期刊论文
2018, 卷号: 103, 期号: 7, 页码: 1160-1168
作者:
Lin, Chi Hua Sarah
;
Zhang, Yu
;
Kaushansky, Kenneth
;
Zhan, Huichun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Bone Marrow Microenvironment
Chronic Myeloproliferative Disorders
Stem Cell Transplantation
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