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上海药物研究所 [6]
复旦大学上海医学院 [4]
武汉大学 [3]
北京大学 [2]
山东大学 [2]
西安交通大学 [1]
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期刊论文 [20]
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Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Gossypol inhibits 5α-reductase 1 and 3α-hydroxysteroid dehydrogenase: Its possible use for the treatment of prostate cancer
期刊论文
Fitoterapia, 2019, 卷号: 133, 页码: 102-108
作者:
Cao S.
;
Wang G.
;
Ge F.
;
Li X.
;
Zhu Q.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
3α-hydroxysteroid dehydrogenase
5α-reductase 1
Gossypol
Mode of action
Retinol dehydrogenase 2
Gossypol inhibits 5 alpha-reductase 1 and 3 alpha-hydroxysteroid dehydrogenase: Its possible use for the treatment of prostate cancer
期刊论文
FITOTERAPIA, 2019, 卷号: 133, 页码: 102-108
作者:
Cao, Shuyan
;
Wang, Guimin
;
Ge, Fei
;
Li, Xiaoheng
;
Zhu, Qiqi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
Gossypol
5 alpha-reductase 1
3 alpha-hydroxysteroid dehydrogenase
Retinol dehydrogenase 2
Mode of action
nAChRs-ERK1/2-Egr-1 signaling participates in the developmental toxicity of nicotine by epigenetically down-regulating placental 11 beta-HSD2
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 344
作者:
Zhou, Jin
;
Liu, Fulin
;
Yu, Luting
;
Xu, Dan
;
Li, Bin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Prenatal nicotine exposure
Placenta
Glucocorticoid
11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2)
Early growth response-1 (Egr-1)
Epigenetics
cAMP/PKA/EGR1 signaling mediates the molecular mechanism of ethanol-induced inhibition of placental 11 beta-HSD2 expression
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 352
作者:
Yu, Luting
;
Zhou, Jin
;
Zhang, Guohui
;
Huang, Wen
;
Pei, Linguo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Prenatal ethanol exposure
Glucocorticoids
Placenta
11 beta-Hydroxysteroid dehydrogenase type 2
cAMP/PKA pathway
Early growth response factor 1
Estrogen Biosynthesis and Its Regulation in Endometriosis
期刊论文
REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2017, 卷号: 1, 期号: 1
作者:
Liu, Xi-Shi
;
Guo, Sun-Wei
;
Qi, Qiu-Ming
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
17 beta-Hydroxysteroid Dehydrogenase Type 2
Aromatase
Endometriosis
Estrogen Biosynthesis
Steroidogenic Acute Regulatory Protein
Estrogen Biosynthesis and Its Regulation in Endometriosis
期刊论文
生殖与发展医学, 2017, 卷号: 1, 期号: 1
作者:
Qi Qiuming
;
Guo Sunwei
;
Liu Xishi
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
17 beta-Hydroxysteroid Dehydrogenase Type 2
Aromatase
Endometriosis
Estrogen Biosynthesis
Steroidogenic Acute Regulatory Protein
Gossypol ameliorates liver fibrosis in diabetic rats induced by high-fat diet and streptozocin
期刊论文
LIFE SCIENCES, 2016, 卷号: 149, 期号: [db:dc_citation_issue], 页码: 58-64
作者:
Chen, Guorong
;
Wang, Rongrong
;
Chen, Hanbin
;
Wu, Liang
;
Ge, Ren-Shan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
Diabetes type 2
Gossypol
Liver fibrosis
High fat diet
11 beta-hydroxysteroid dehydrogenase
Human 3 alpha-hydroxysteroid dehydrogenase type 3: structural clues of 5 alpha-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth
期刊论文
BIOCHEMICAL JOURNAL, 2016, 卷号: 473
作者:
Zhang, Bo
;
Hu, Xiao-Jian
;
Wang, Xiao-Qiang
;
Theriault, Jean-Francois
;
Zhu, Dao-Wei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
aldo-keto reductase 1C2 (AKR1C2)
cancer cell growth
crystal structure
5 alpha-dihydrotestosterone (5 alpha-DHT)
3 alpha-hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3)
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity
期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2014, 卷号: 141
作者:
Zhang, Bo
;
Zhu, Dao-Wei
;
Hu, Xiao-Jian
;
Zhou, Ming
;
Shang, Peng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
3-Alpha hydroxysteroid dehydrogenase
AKR1C2
20 alpha-HSD
Mutation
Kinetics
Crystal structure
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