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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载:34/0  |  提交时间:2021/12/01
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:  Jiang, Min;  Peng, Lei;  Yang, Kai;  Wang, Tianqi;  Yan, Xueming
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng;  Gao, Lixin
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01
3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation 期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10
作者:  Hu, Yuanyuan;  Gao, Anhui;  Liao, Honghui;  Zhang, Mengmeng;  Xu, Gaoya
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3 beta inhibitors and neuroprotective agents 期刊论文
PHARMAZIE, 2017, 卷号: 72, 期号: 12, 页码: 707-713
作者:  Hu, Yuanyuan;  Ruan, Wenchen;  Gao, Anhui;  Zhou, Yubo;  Gao, Lixin
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
A redox mechanism underlying nucleolar stress sensing by nucleophosmin 期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:  Yang, Kai;  Wang, Ming;  Zhao, Yuzheng;  Sun, Xuxu;  Yang, Yi
收藏  |  浏览/下载:47/0  |  提交时间:2019/01/08
A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway 期刊论文
中国药理学报:英文版, 2016, 卷号: 000, 期号: 006, 页码: 741
作者:  Pang Tao;  Wang Yunjie;  Gao Yuanxue;  Xu Yuan;  Li Qiu
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
anovelgsk3inhibitoryq138preventsneuronalinjuryinducedbyglutamateandbrainischemiathroughactivationofthenrf2signalingpathway 期刊论文
actapharmacologicasinica, 2016, 卷号: 000, 期号: 006, 页码: 741
作者:  Pang Tao;  Wang Yunjie;  Gao Yuanxue;  Xu Yuan;  Li Qiu
收藏  |  浏览/下载:3/0  |  提交时间:2020/07/01
Synthesis and Evaluation of 3-(furo[2,3-b]pyridin-3-yl)-4-(1H-indol-3-yl)-maleimides as Novel GSK-3 Inhibitors and Anti-Ischemic Agents 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 746-752
作者:  Ye, Qing;  Li, Qiu;  Zhou, Yubo;  Xu, Lei;  Mao, Weili
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Synthesis and biological evaluation of 3-([1,2,4]triazolo [4,3-a]pyridin-3-yl)-4-(indol-3-yl)-maleimides as potent, selective GSK-3 beta inhibitors and neuroprotective agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 5, 页码: 1179-1188
作者:  Ye, Qing;  Mao, Weili;  Zhou, Yubo;  Xu, Lei;  Li, Qiu
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08


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