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上海药物研究所 [6]
昆明植物研究所 [3]
大连理工大学 [2]
合肥物质科学研究院 [2]
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期刊论文 [23]
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2020 [23]
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Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta
期刊论文
STEROIDS, 2020, 卷号: 161, 页码: 5
作者:
Liu, Jiao
;
Wu, Xin
;
Yang, Min
;
Gu, Yu-Cheng
;
Yao, Li-Gong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
Sinularia erecta
Steroidal derivative
Cytotoxicity
Baeyer-Villiger oxidation
Low-frequency fiber optic hydrophone based on weak value amplification
期刊论文
OPTICS EXPRESS, 2020, 卷号: 28, 期号: 18, 页码: 25935-25948
作者:
Luo, Zhengchun
;
Yang, Yue
;
Wang, Zhongmin
;
Yu, Miao
;
Wu, Chongjian
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/01
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
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  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
Sources and a proposal for comprehensive exploitation of lithium brine deposits in the Qaidam Basin on the northern Tibetan Plateau, China Evidence from Li isotopes
期刊论文
ORE GEOLOGY REVIEWS, 2020, 卷号: 117
作者:
He, Mao-Yong
;
Luo, Chong-Guang
;
Yang, Hong-Jun
;
Kong, Fan-Cui
;
Li, Yu-Long
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2021/11/22
Short- and medium-chain chlorinated paraffins in aquatic organisms from an e-waste site: Biomagnification and maternal transfer
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 708, 页码: 8
作者:
Guan, Ke-Lan
;
Liu, Yu
;
Luo, Xiao-Jun
;
Zeng, Yan-Hong
;
Mai, Bi-Xian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/11/19
Tube-cantilever double resonance enhanced fiber-optic photoacoustic spectrometer
期刊论文
Optics and Laser Technology, 2020, 卷号: 123
作者:
Chen, Ke
;
Deng, Hong
;
Guo, Min
;
Luo, Chen
;
Liu, Shuai
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/11/29
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