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科研机构
山东大学 [41]
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期刊论文 [40]
会议论文 [1]
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2019 [1]
2017 [3]
2016 [6]
2015 [4]
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2013 [6]
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专题:山东大学
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Protective effects of tetramethylpyrazine analogue Z-11 on cerebral ischemia reperfusion injury
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 卷号: 844, 页码: 156-164
作者:
Zhai Li
;
Jia Yulei
;
Ji Yaqing
;
Zou Jinmin
;
Liu Xinyong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Cerebral ischemia
Tetramethylpyrazine
Reactive oxygen species
Novel diaryltriazines with a picolinonitrile moiety as potent HIV-1 RT inhibitors: a patent evaluation of WO2016059647(A2)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 1, 页码: 9-15
作者:
Huang, Boshi
;
Zhou, Zhongxia
;
Kang, Dongwei
;
Li, Wanzhuo
;
Chen, Zihui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/16
Diaryltriazine
HIV-1 RT inhibitors
picolinonitrile
modeling
simulation
highly conserved residues
Tetramethylpyrazine Analogue CXC195 Protects Against Dopaminergic Neuronal Apoptosis via Activation of PI3K/Akt/GSK3 beta Signaling Pathway in 6-OHDA- Induced Parkinson's Disease Mice
期刊论文
NEUROCHEMICAL RESEARCH, 2017, 卷号: 42, 期号: 4, 页码: 1141-1150
作者:
Chen, Lin
;
Cheng, Li
;
Wei, Xinbing
;
Yuan, Zheng
;
Wu, Yanmei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Tetramethylpyrazine analogue CXC195
6-OHDA
Parkinson's disease
Apoptosis
PI3K/Akt/GSK3 beta pathway
Randomized controlled trial: Standard versus supplemental bowel preparation in patients with Bristol stool form 1 and 2
期刊论文
PLOS ONE, 2017, 卷号: 12, 期号: 2
作者:
Li, Yueyue
;
Jia, Xinyong
;
Liu, Baozhen
;
Qi, Yanmei
;
Zhang, Xiubin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/12
Discovery of novel anti-HIV agents via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry-based approach
期刊论文
EXPERT OPINION ON DRUG DISCOVERY, 2016, 卷号: 11, 期号: 9, 页码: 857-871
作者:
Gao, Ping
;
Sun, Lin
;
Zhou, Junsu
;
Li, Xiao
;
Zhan, Peng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/16
CuAAC
click chemistry
drug design
HIV inhibitors
triazole
Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 3, 页码: 380-385
作者:
Li, Wenxin
;
Huang, Boshi
;
Kang, Dongwei
;
De Clercq, Erik
;
Daelemans, Dirk
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/16
anti-HIV-1 activity
drug design
HIV-1
NNRTIs
S-DABOs
An improved synthesis approach of the HIV-1 inhibitor RDEA427, a pyrrolo[2,3-d]pyrimidine derivative
期刊论文
ARKIVOC, 2016, 页码: 45-51
作者:
Huang, Boshi
;
Liu, Xinhao
;
Li, Wanzhuo
;
Chen, Zihui
;
Kang, Dongwei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
HIV-1 inhibitor
RDEA427
diarylpyrimidine-like derivative
increased
overall yield
environment-friendly
Design, Synthesis, and Biological Evaluation of Novel 2-(Pyridin-3-yloxy)acetamide Derivatives as Potential Anti-HIV-1 Agents
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 87, 期号: 2, 页码: 283-289
作者:
Huang, Boshi
;
Li, Xiao
;
Zhan, Peng
;
De Clercq, Erik
;
Daelemans, Dirk
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
anti-HIV activity
bioisosterism
HIV-1 RT
molecular hybridization
non-nucleoside reverse transcriptase inhibitors
Arylazolyl(azinyl)thioacetanilides: Part 19: Discovery of Novel Substituted Imidazo[4,5-b]pyridin-2-ylthioacetanilides as Potent HIV NNRTIs Via a Structure-based Bioisosterism Approach
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 2, 页码: 241-253
作者:
Li, Xiao
;
Huang, Boshi
;
Zhou, Zhongxia
;
Gao, Ping
;
Pannecouque, Christophe
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
antiviral activity
drug design
HIV
imidazo[4,5-b]pyridin-2-ylthioacetanilides
molecular modeling
NNRTIs
SAR
Substituted indoles as HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent evaluation (WO2015044928)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 5, 页码: 629-635
作者:
Li, Xiao
;
Gao, Ping
;
Zhan, Peng
;
Liu, Xinyong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
HIV
non-nucleoside reverse transcriptase inhibitors
substituted
indole
heterocycle
antiviral activity
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