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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 专题：山东大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors 期刊论文 MEDCHEMCOMM, 2018, 卷号: 9, 期号: 1, 页码: 149-159 作者:  Wu, Gaochan;  Gao, Yun;  Kang, Dongwei;  Huang, Boshi;  Huo, Zhipeng 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/11 Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014-2017) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2018, 卷号: 28, 期号: 4, 页码: 299-316 作者:  Zuo, Xiaofang;  Huo, Zhipeng;  Kang, Dongwei;  Wu, Gaochan;  Zhou, Zhongxia 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 HIV-1  AIDS  inhibitors  drug design  medicinal chemistry  hit-to-lead  optimization   Design, synthesis, and antiviral evaluation of novel hydrazone-substituted thiophene[3,2-d]pyrimidine derivatives as potent human immunodeficiency virus-1 inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 6, 页码: 2009-2021 作者:  Wang, Zhao;  Kang, Dongwei;  Chen, Meng;  Wu, Gaochan 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 backbone-binding  diarylpyrimidine  HIV-1  molecular simulation  NNRTIs  thiophene[3,2-d]pyrimidine   Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel" 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 6, 页码: 1014-1028 作者:  Zhou, Zhongxia;  Liu, Tao;  Kang, Dongwei;  Huo, Zhipeng;  Wu, Gaochan 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 4, 页码: 370-375 作者:  Kang, Dongwei;  Wang, Zhao;  Zhang, Heng;  Wu, Gaochan;  Zhao, Tong 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/11 HIV-1  NNRTIs  DAPY  tolerant regions  drug design   Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding Site 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 4, 页码: 334-338 作者:  Huo, Zhipeng;  Zhang, Heng;  Kang, Dongwei;  Zhou, Zhongxia;  Wu, Gaochan 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/11 HIV-1  AIDS  NNRTIs  drug design  "NNRTI Adjacent" binding site   Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 4, 页码: 383-391 作者:  Kang, Dongwei;  Huo, Zhipeng;  Wu, Gaochan;  Xu, Jiabao;  Zhan, Peng 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/12 HIV-1  NNRTI  diarylpyrimidine  fused pyrimidine  isoquinoline   Discovery of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the Tolerant Region I of NNIBP 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 11, 页码: 1188-1193 作者:  Kang, Dongwei;  Ding, Xiao;  Wu, Gaochan;  Huo, Zhipeng;  Zhou, Zhongxia 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/12 HIV-1  NNRTIs  thiophene(3,2-d]pyrimidine  tolerant region I  drug  design   Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 10, 页码: 4424-4443 作者:  Kang, Dongwei;  Fang, Zengjun;  Huang, Boshi;  Lu, Xueyi;  Zhang, Heng 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/12 Discovery of uracil-bearing DAPYs derivatives as novel HIV-1 NNRTIs via crystallographic overlay-based molecular hybridization 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 130, 页码: 209-222 作者:  Zhang, Heng;  Tian, Ye;  Kang, Dongwei;  Huo, Zhipeng;  Zhou, Zhongxia 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/12 NNRTIs  DAPYs  Uracil  Molecular hybridization  Physicochemical  properties  Drug design