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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 专题：湖南农业大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Lead induces apoptosis in mouse TM3 Leydig cells through the Fas/FasL death receptor pathway 期刊论文 Environmental Toxicology and Pharmacology, 2017, 卷号: 56, 页码: 99-105 作者:  He, Xiuyuan;  Wu, Jing*;  Yuan, Liyun;  Lin, Feng*;  Yi, Jine 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/23 Lead  TM3 leydig cells  Cytotoxicity  Apoptosis  Fas/FasL  Caspase-8   Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice 期刊论文 Journal of veterinary science, 2014, 卷号: 15, 期号: 1, 页码: 141-148 作者:  Yi, Jine*;  Xia, Wei;  Wu, Jianping;  Yuan, Liyun;  Wu, Jing 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 alcohol  antioxidant capacity  betulinic acid  lipid peroxidation  liver damage   Arsanilic acid causes apoptosis and oxidative stress in rat kidney epithelial cells (NRK-52e cells) by the activation of the caspase-9 and -3 signaling pathway 期刊论文 Drug and Chemical Toxicology, 2014, 卷号: 37, 期号: 1, 页码: 55-62 作者:  Lu, Yin;  Yuan, Hui;  Deng, Sijun;  Wei, Qiang;  Guo, Chengzhi 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/23 Apoptosis  Arsanilic acid  Caspase-3 and -9  Mitochondria  NRK-52e cells  Reactive oxygen species   Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway 期刊论文 Journal of veterinary science (Suwŏn-si, Korea), 2013, 卷号: 14, 期号: 3, 页码: 281-289 作者:  Deng, Sijun;  Yuan, Hui*;  Yi, Jine;  Lu, Yin;  Wei, Qiang 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/23 apoptosis  gossypol acetic acid  mitochondrial signaling pathway   DNA damage and decrease of cellular oxidase activity in piglet Sertoli cells exposed to arsanilic acid. 期刊论文 The Journal of veterinary medical science, 2011, 卷号: 73, 期号: 2, 页码: 199-203 作者:  Zhang, Ming;  He, Zuping;  Yuan, Hui*;  Zhu, Li;  Guo, Chengzhi 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 arsanilic acid  DNA damage  oxidase activity  piglet Sertoli cells  toxicity   DNA damage and decrease of cellular oxidase activity in piglet sertoli cells exposed to gossypol 期刊论文 African Journal of Biotechnology, 2011, 卷号: 10, 期号: 14, 页码: 2797-2802 作者:  Zhang, Ming;  Yuan, Hui*;  He, Zuping;  Yuan, Liyun;  Yi, Jine 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/23 Gossypol  sertoli cells  oxidase  DNA damage   Cadmium suppresses the proliferation of piglet Sertoli cells and causes their DNA damage, cell apoptosis and aberrant ultrastructure 期刊论文 Reproductive Biology and Endocrinology, 2010, 卷号: 8, 期号: 1, 页码: 97 作者:  Zhang, Ming;  He, Zuping*;  Wen, Lixin;  Wu, Jing;  Yuan, Liyun 收藏  |  浏览/下载：1/0  |  提交时间：2019/12/23 Cadmium  Male Germ Cell  Seminiferous Tubule  Sertoli Cell  Spermatogonial Stem Cell   Functional analyses of ethylene response factor JERF3 with the aim of improving tolerance to drought and osmotic stress in transgenic rice 期刊论文 Transgenic Research, 2010, 卷号: 19, 期号: 5, 页码: 809-818 作者:  Haiwen Zhang;  Wu Liu;  Liyun Wan;  Fang Li;  Liangying Dai 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 Drought  ERF protein JERF3  Osmotic stress  Rice  Transcriptional regulation   Gynostemma pentaphyllum protects mouse male germ cells against apoptosis caused by zearalenone via Bax and Bcl-2 regulation 期刊论文 Toxicology Mechanisms and Methods, 2010, 卷号: 20, 期号: 3, 页码: 153-158 作者:  Yuan, Hui;  Deng, Youtian;  Yuan, Liyun;  Wu, Jing;  Yuan, Zhihang 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 Gynostemma pentaphyllum  anti-toxicity  Zearalenone  male germ cells  Bax and Bcl-2   Generation and characterization of a monoclonal antibody to penicillic acid from Penicillium cyclopium 期刊论文 AFRICAN JOURNAL OF BIOTECHNOLOGY, 2010, 卷号: 9, 期号: 21, 页码: 3026-3031 作者:  Lei, Hongyu;  He, Zuping;  Yuan, Hui*;  Wu, Jing;  Wen, Lixin 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/23 Penicillic acid is one of the main mycotoxins in moldy feedstuff and has toxic effect on livestock and poultry and probably humans due to food chain transmission. The objective of this study was to generate and characterize a monoclonal antibody to penicillic acid for the efficient detection of penicillic acid from Penicillium cyclopiumby immunological methods. To this end  penicillic acid was conjugated to bovine serum album (BSA) using the Mannich reaction and coupled with ovalbumin (OVA) by the method of 1-ethyl-3-(3-dimethyl-aminopropyl) carbodiimide hydrochloride (EDC) to generate artificial antigens penicillic acid-BSA and penicillic acid-OVA. A hybridoma cell line was obtained after fusion of mouse SP2/0 myeloma cells with spleen cells of BALB/c mice immunized with artificial antigen penicillic acid-BSA. A monoclonal antibody specific against penicillic acid was produced in vivo by this hybridoma cell line. Further analysis revealed that the monoclonal antibody to penicillic acid was of the IgG1 subtype  with a titer of 1: 2.05 × 105. The antibody to penicillic acid had no or less cross-reaction with mycotoxins  including aflatoxin B1  zearalenone  T-2 toxin and fumonisins and more importantly  it assumed an affinity of about 1.54 × 108 liters per mol. Our ability to produce a monoclonal antibody to penicillic acid provides necessary groundwork for the effective detection of penicillic acid in various tissues of animals and human  using the immunocytochemistry  Western blots and enzyme-linked immunosorbent assay (ELISA).