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科研机构
上海药物研究所 [19]
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期刊论文 [18]
会议论文 [1]
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2020 [2]
2019 [1]
2017 [2]
2016 [2]
2015 [2]
2014 [5]
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A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice
期刊论文
Oncotarget, 2017, 卷号: 8, 期号: 57, 页码: 97137-97152
作者:
Li, Yi-Fei
;
Wu, Jia-Sheng
;
Li, Yuan-Yuan
;
Dai, Yan
;
Zheng, Min
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Zhang, Jing
;
Li, Huating
;
Zhou, Hu
;
Fang, Li
;
Xu, Jingjing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:
Ma, Shan-yao
;
Ning, Meng-meng
;
Zou, Qing-an
;
Feng, Ying
;
Ye, Yang-liang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
OL3
MN6
linagliptin
TGR5 agonist
DPP4 inhibitor
GLP-1
low-absorbed
gallbladder filling
type 2 diabetes mellitus
Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 3, 页码: 415-424
作者:
Ma, Lei-lei
;
Wu, Zhi-tao
;
Wang, Le
;
Zhang, Xue-feng
;
Wang, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
leflunomide
hepatotoxicity
CYPs
teriflunomide
aminobenzotriazole
proadifen
NTCP
cholestasis
Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2015, 卷号: 43, 期号: 11, 页码: 1751-9
作者:
Li, Xiuli
;
Zhong, Kan
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior
期刊论文
Frontiers in behavioral neuroscience, 2015, 卷号: 9, 页码: 70
作者:
Huang, Fei
;
Wang, Tingting
;
Lan, Yunyi
;
Yang, Li
;
Pan, Weihong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham
期刊论文
Analytical and bioanalytical chemistry, 2014, 卷号: 406, 期号: 29, 页码: 7715-27
作者:
Xiong, Aizhen
;
Fang, Lianxiang
;
Yang, Xiao
;
Yang, Fan
;
Qi, Meng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
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