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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2019     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785 作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng 收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01 PRMT5 inhibitor  Anti-proliferative  Cellular target validation  Design and synthesis   Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433 作者:  Guo, Zuhao;  Zhang, Zhuqing;  Yang, Hong;  Cao, Danyan;  Xu, Xiaowei 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文 CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388 作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 virtual screening  epigenetic inhibitor  antiproliferation  molecular docking   A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114 作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng 收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01 Arginine methylation  Protein arginine methyltransferases (PRMTs)  small molecule inhibitors  drug research and development   The arginine methyltransferase PRMT5 and PRMT1 distinctly regulate the degradation of anti-apoptotic protein CFLAR(L) in human lung cancer cells 期刊论文 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1 作者:  Li, Mingyue;  An, Wentao;  Xu, Linyan;  Lin, Yidan;  Su, Ling 收藏  |  浏览/下载：31/0  |  提交时间：2019/12/11 CFLAR  PRMT1  PRMT5  ITCH  Apoptosis   Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha 期刊论文 THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617 作者:  Zheng, Bai-Nan;  Ding, Chen-Hong;  Chen, Shi-Jie;  Zhu, Kongkai;  Shao, Jingwei 收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 PRMT5  HNF4 alpha  hepatocellular carcinoma  cancer stem cells