CORC

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CORC

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SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：35/0  |  提交时间：2021/05/24
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载：45/0  |  提交时间：2021/05/24
A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling 期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:  Bu, Wenxuan;  Li, Bo;  Feng, Lijin;  Feng, Qilin;  Hu, Ke
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Artemisinin analog SM934 ameliorates dextran sulfate sodium-induced chronic colitis through regulating CD4+T cell proliferation and differentiation via mTORC1 pathway 期刊论文
EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 卷号: 49, 页码: 899-899
作者:  Shao, M.
收藏  |  浏览/下载：70/0  |  提交时间：2020/07/01
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:  Kong, Yuanyuan;  Li, Bo;  Chang, Shuaikang;  Gao, Lu;  Xu, Zhijian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 2, 页码: 823-834
作者:  Xie, Yongsheng;  Li, Bo;  Bu, Wenxuan;  Gao, Lu;  Zhang, Yong
收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Dual inhibition of mTORC1/2 by DCZ0358 induces cytotoxicity in multiple myeloma and overcomes the protective effect of the bone marrow microenvironment 期刊论文
CANCER LETTERS, 2018, 卷号: 421, 页码: 135-144
作者:  Gao, Lu;  Li, Bo;  Yang, Guang;  Liu, Peng;  Lan, Xiucai
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition 期刊论文
CANCER LETTERS, 2017, 卷号: 406, 页码: 105-115
作者:  Sun, Danni;  Liu, Hongchun;  Dai, Xiaoyang;  Zheng, Xingling;  Yan, Juan
收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:  Qian, Jianchang;  Chen, Yaqing;  Meng, Tao;  Ma, Lanping;  Meng, Lanfang
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08

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