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复旦大学上海医学院 [13]
山东大学 [6]
武汉大学 [6]
上海药物研究所 [5]
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高能物理研究所 [5]
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期刊论文 [70]
学位论文 [5]
会议论文 [2]
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2017 [77]
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Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
Li, Xiaokang
;
Wang, Huan
;
Xu, Yixiang
;
Liu, Wenwen
;
Gong, Qi
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Graphene oxide-iron oxide nanocomposite as an inhibitor of a beta 42 amyloid peptide aggregation
期刊论文
Colloids and surfaces b-biointerfaces, 2017, 卷号: 159, 页码: 540-545
作者:
Ahmad, Israr
;
Mozhi, Anbu
;
Yang, Lin
;
Han, Qiusen
;
Liang, Xingjie
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/04/23
Graphene oxides
Nanocomposites
Amyloid peptide
Aggregation
Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Lipid Metabolism in Aging Adults
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2017, 卷号: 9, 期号: 0, 页码: 334-340
作者:
Ren, Weicong
;
Ma, Jiang
;
Li, Juan
;
Zhang, Zhijie
;
Wang, Mingwei
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2017/11/22
rTMS
older adults
cardiovascular disease
lipid metabolism
HPT axis
PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering A beta generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 46, 页码: 81001-81013
作者:
Huang, Na
;
Lu, Shuai
;
Liu, Xiao-Ge
;
Zhu, Jie
;
Wang, Yu-Jiong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2017/11/27
Alzheimer's Disease
Nanoparticles
Beta-amyloid
Curcumin
Peptide
Magnetic resonance spectroscopy analysis of neurochemical changes in the atrophic hippocampus of app/ps1 transgenic mice
期刊论文
Behavioural brain research, 2017, 卷号: 335, 页码: 26-31
作者:
Liang, Shengxiang
;
Huang, Jia
;
Liu, Weilin
;
Jin, Hao
;
Li, Long
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/04/23
Alzheimer's disease
Neurochemical metabolism
Hippocampus
N-acetylaspartate
Magnetic resonance spectroscopy
Amyloid beta: structure, biology and structure-based therapeutic development
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235
作者:
Chen, Guo-fang
;
Xu, Ting-hai
;
Yan, Yan
;
Zhou, Yu-ren
;
Jiang, Yi
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
amyloid beta peptide
amyloid precursor protein
Alzheimer's disease
neurodegenerative diseases
drug discovery
(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Li, Wan
;
Liu, Huihui
;
Jiang, Hanjie
;
Wang, Chen
;
Guo, Yongfei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2018/05/25
Alterations in resting-state functional connectivity of the default mode network in amnestic mild cognitive impairment: an fmri study
期刊论文
Bmc medical imaging, 2017, 卷号: 17, 页码: 8
作者:
Li, Moyi
;
Zheng, Guohua
;
Zheng, Yuhui
;
Xiong, Zhenyu
;
Xia, Rui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/04/23
Amnestic mild cognitive impairment
Default mode network
Functional magnetic resonance imaging
Functional connectivity
Independent component analysis
Nonparametric and semiparametric estimation of quantile residual lifetime for length-biased and right-censored data
期刊论文
CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE, 2017, 卷号: 45, 期号: 2, 页码: 220-250
作者:
Wang, Yixin
;
Zhou, Zhefang
;
Zhou, Xiao-Hua
;
Zhou, Yong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2018/07/30
Cox model
length-bias
quantile residual lifetime model
right-censoring
Nonparametric and semiparametric estimation of quantile residual lifetime for length-biased and right-censored data
期刊论文
CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE, 2017, 卷号: 45, 期号: 2, 页码: 220-250
作者:
Wang, Yixin
;
Zhou, Zhefang
;
Zhou, Xiao-Hua
;
Zhou, Yong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/08/22
Cox model
length-bias
quantile residual lifetime model
right-censoring
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