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科研机构
上海药物研究所 [19]
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期刊论文 [19]
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2018 [1]
2017 [2]
2016 [2]
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Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
期刊论文
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 6, 页码: 593-603
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhong, Kan
;
Guo, Zitao
;
Li, Xiuli
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 203, 页码: 110-119
作者:
To, Kenneth K. W.
;
Wu, Xu
;
Yin, Chun
;
Chai, Stella
;
Yao, Sheng
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  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
ABCG2
Multidrug resistance
Marsdenia tenacissima
MRP1
P-glycoprotein
Polyoxypregnane compounds
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
期刊论文
Scientific Reports, 2016, 卷号: 6
作者:
Ni, Xuan
;
Gao, Yimeng
;
Wu, Zhitao
;
Ma, Leilei
;
Chen, Chen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 8, 页码: 9389-9404
作者:
Chen, Gang
;
Liu, Junhua
;
Chen, Wantao
;
Xu, Qin
;
Xiao, Meng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
multi-drug resistance
ABCB1
chemotherapy
apoptosis
panax ginseng
Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 627-643
作者:
Tian, Dan-dan
;
Jia, Wei-wei
;
Liu, Xin-wei
;
Wang, Dan-dan
;
Liu, Jun-hua
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
tanshinol
methylation
catechol-O-methyltransferase
herb-drug interaction
Salvia miltiorrhiza roots
Danshen
HDAC inhibitor-induced drug resistance involving ATP-binding cassette transporters
期刊论文
ONCOLOGY LETTERS, 2015, 卷号: 9, 期号: 2, 页码: 515-521
作者:
Ni, Xuan
;
Li, L.
;
Pan, Guoyu
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
histone deacetylase inhibitors
cancer treatment
multidrug resistance
P-glycoprotein
breast cancer resistance protein
multidrug resistance protein 1/2
nuclear receptor
Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 9, 页码: 1188-1198
作者:
Wu, Zhi-tao
;
Qi, Xin-ming
;
Sheng, Jing-jing
;
Ma, Lei-lei
;
Ni, Xuan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
timosaponin A3
hepatotoxicity
cholestasis
bile acid
transporter
Cyp7a1
ROS
N-acetyl-L-cysteine
mangiferin
Are Circulating Metabolites Important in Pharmacokinetic Drug-Drug Interactions? A Retroanalysis of Clinical Data
期刊论文
CURRENT DRUG METABOLISM, 2014, 卷号: 15, 期号: 8, 页码: 767-790
作者:
Zhao, Yuan-Sheng
;
Chen, Feng
;
Li, Li
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  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Human drug metabolites
inhibitory roles
official investigation guidance
pharmacokinetic drug-drug interactions
Effects of efflux transporters on disposition of tyrosine kinase inhibitors
期刊论文
Journal of International Pharmaceutical Research, 2014, 卷号: 41, 期号: 1, 页码: 75-82
作者:
Lin Lishan
;
Chen Xiaoyan
;
Zhong Dafang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
efflux transporter
tyrosine kinase inhibitors
disposition
genetic polymorphism
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