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科研机构
上海药物研究所 [12]
合肥物质科学研究院 [9]
海洋研究所 [4]
兰州理工大学 [2]
烟台海岸带研究所 [2]
西北高原生物研究所 [1]
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期刊论文 [28]
学位论文 [3]
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2021 [31]
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Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis
期刊论文
BIOENGINEERED, 2021, 卷号: 12
作者:
Zhang, Runze
;
Lian, Yanhong
;
Xie, Kangjie
;
Cai, Yunfang
;
Pan, Yafei
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
Ropivacaine
hepatocellular carcinoma
IGF-1R
IGF1R-PI3K-AKT-mTOR signaling
cell cycle
epithelial-mesenchymal transition
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
作者:
Wu, Ning
;
Li, Zhi
;
Wang, Jing
;
Geng, Lihua
;
Yue, Yang
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  |  
浏览/下载:57/0
  |  
提交时间:2021/12/02
Fucoidans
COVID-19
Pulmonary fibrosis
Epithelial-mesenchymal transition
TGF-beta
PI3K/AKT pathway
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
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  |  
浏览/下载:39/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Cardiotoxicity of Epidermal Growth Factor Receptor 2-Targeted Drugs for Breast Cancer
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:
Yang, ZiYan
;
Wang, Wei
;
Wang, Xiaojia
;
Qin, ZhiQuan
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  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
cardiotoxicity
ErbB2
targeting drugs
breast cancer
therapy
Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
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  |  
浏览/下载:54/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
;
Tan, Xinyue
;
Wang, Shuang
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  |  
浏览/下载:55/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Wortmannine H, a phenylpentenol isolated from an endophytic fungus, Talaromyces wortmannii LGT-4
期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 19, 页码: 3204-3209
作者:
Li, Xiao-Fei
;
Yang, Zhong-Duo
;
Yang, Xing
;
Yang, Li-Jun
;
Yao, Xiao-Jun
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  |  
浏览/下载:12/0
  |  
提交时间:2021/10/14
Wortmannine
endophytic fungus
Talaromyces wortmannii
Tripterygium wilfordii
A norbisabolane and an arabitol benzoate from Talaromyces marneffei, an of
期刊论文
FITOTERAPIA, 2021, 卷号: 153
作者:
Yang, Zhong-Duo
;
Zhang, Xu-Dong
;
Yang, Xing
;
Yao, Xiao-Jun
;
Shu, Zong-Mei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/10/14
Endophytic fungus
Talaromyces marneffei
Secondary metabolites
Structure elucidation
The Role of Apoptosis Pathway in the Cytotoxicity Induced by Fresh and Aged Zinc Oxide Nanoparticles
期刊论文
Nanoscale Research Letters, 2021, 卷号: 16
作者:
Wang,Juan
;
Wang,Lei
;
Zhao,Wenting
;
Yu,Na
;
Cheng,Meiling
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/08/31
Aged zinc oxide nanoparticles
Cytotoxicity
Mechanism
Apoptosis
Transcriptomics
Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 121, 页码: 10
作者:
Han, Yijing
;
Zhang, Qianqian
;
Chen, Lizhu
;
Yang, Dinglong
;
Zhao, Jianmin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/10/20
Ruditapes philippinarum
Extracellular traps
Reactive oxygen species
Mitochondria
Antibacterial activity
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