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科研机构
上海药物研究所 [15]
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期刊论文 [15]
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2020 [3]
2019 [1]
2018 [1]
2016 [1]
2015 [2]
2011 [2]
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Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56
作者:
Xu, Xiaoju
;
Xu, Xu
;
Hao, Yanping
;
Zhu, Xialin
;
Lu, Jian
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
DW14006 as a Direct AMPK alpha Activator Ameliorates Diabetic Peripheral Neuropathy in Mice
期刊论文
DIABETES, 2020, 卷号: 69, 期号: 9, 页码: 1974-1988
作者:
Xu, Xu
;
Wang, Wei
;
Wang, Zhengyu
;
Lv, Jianlu
;
Xu, Xiaoju
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
Structural elucidation of a pectin from roots of Polygala tenuifolia and its neuritogenesis inducing activity in PC12 cells
期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 236, 页码: 9
作者:
Zeng, Hui
;
Huang, Lulin
;
Tao, Hong
;
Zhang, Yiwen
;
Ding, Kan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Polygala tenuifolia
Pectin
Neuritogenesis
Neurodegenerative disorders
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:
Wang, Zhenkang
;
Ma, Chunhua
;
Wang, Yujie
;
Xiao, Qiang
;
Xu, Chenghui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Gentisides
Neurotrophic activity
Isosteric replacement
Conformational restriction
PC 12 cells
Chemoenzymatically synthesized GM3 analogues as potential therapeutic agents to recover nervous functionality after injury by inducing neurite outgrowth
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 146, 页码: 613-620
作者:
Zheng, Changping
;
Qu, Huanhuan
;
Liao, Wenfeng
;
Bavaro, Teodora
;
Terreni, Marco
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Ganglioside GM3
Chemoenzymatic synthesis
PC12 cells
Neurite outgrowth
Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant Activity
期刊论文
CNS NEUROSCIENCE & THERAPEUTICS, 2016, 卷号: 22, 期号: 5, 页码: 368-377
作者:
Wang, Yun
;
Guo, Lin
;
Jiang, Hua-Feng
;
Zheng, Long-Tai
;
Zhang, Ao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Allosteric modulation
Antidepressant
Brain-derived neurotrophic factor
Glycogen synthase kinase 3
Sigma-1 receptors
Connexin 43 stabilizes astrocytes in a stroke-like milieu to facilitate neuronal recovery
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 8, 页码: 928-938
作者:
Wu, Le-yu
;
Yu, Xue-li
;
Feng, Lin-yin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
astrocytes
Connexin 43
oxygen-glucose deprivation/recovery
middle cerebral artery occlusion
CREB
Ephrin-A4
calcium
Protein Kinase A Rescues Microtubule Affinity-regulating Kinase 2-induced Microtubule Instability and Neurite Disruption by Phosphorylating Serine 409
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 5, 页码: 3149-3160
作者:
Deng, Si-Si
;
Wu, Le-Yu
;
Wang, Ya-Chao
;
Cao, Peng-Rong
;
Xu, Lei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Microtubule
Microtubule-associated Protein (MAP)
Neurite Outgrowth
Protein Kinase A (PKA)
Tau Protein (Tau)
MARK2
Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway
期刊论文
BIOCHEMICAL JOURNAL, 2011, 卷号: 440, 页码: 273-282
作者:
Cui, Hengxiang
;
Shao, Chenghao
;
Liu, Qin
;
Yu, Wenjie
;
Fang, Jianping
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
heparanase
neurite outgrowth
neuritogenesis
neuron differentiation
p38 mitogen-activated protein kinase (MAPK)
Iridoids from leaves of Gelsemium elegans
期刊论文
Phytochemistry, 2011, 卷号: 72, 期号: 9, 页码: 916-22
作者:
Zhang, Bin-Feng
;
Zhang, Qiu-Ping
;
Liu, Hai
;
Chou, Gui-Xin
;
Wang, Zheng-Tao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
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