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科研机构
大连化学物理研究所 [90]
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期刊论文 [87]
会议论文 [3]
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2019 [7]
2018 [9]
2017 [4]
2016 [5]
2015 [6]
2014 [8]
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物理化学 [15]
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Biflavones from Ginkgo biloba as inhibitors of human thrombin
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92, 页码: 10
作者:
Chen, Tian-Ran
;
Wei, Ling-Hua
;
Guan, Xiao-Qing
;
Huang, Chao
;
Liu, Zhe-Yi
收藏
  |  
浏览/下载:143/0
  |  
提交时间:2019/12/02
Ginkgo biloba
Thrombin
Proteolytic activity
Biflavones
Inhibitory effects
Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Ren, Xiaoqian
;
Giesy, John P.
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/12/02
SCCPs
Mode of action
PPAR alpha
Luciferase assay
Molecular docking
Metabolomics
Characterization of the substrate scope of an alcohol dehydrogenase commonly used as methanol dehydrogenase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 12, 页码: 1446-1449
作者:
Feng, Yanbin
;
Guo, Xiaojia
;
Wang, Xueying
;
Liu, Yuxue
;
Liu, Wujun
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/06/20
Alcohol dehydrogenase
Substrate preference
Methanol dehydrogenase
Geobacillus stearothermophilus
Molecular docking
Cofactor regeneration
Combining an in silico approach with an animal experiment to investigate the protective effect of troxerutin for treating acute lung injury
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 11
作者:
Li, Ying
;
Ma, Pan
;
Fu, Jin
;
Wu, Jingjing
;
Wu, Xue
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/12/02
Troxerutin
In silico prediction
Acute lung injury
Protective effect
Inflammatory response
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Methyl-Hispolon from Phellinus lonicerinus (Agaricomycetes) Affects Estrogen Signals in MCF-7 Breast Cancer Cells and Premature Aging in Rats
期刊论文
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS, 2019, 卷号: 21, 期号: 4, 页码: 381-392
作者:
Lv, Huifang
;
Chen, Beiyan
;
Huang, Wenfeng
;
Wang, Ailing
;
Liu, Lanqing
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
methyl-hispolon
estrogen signals
phytoestrogen
hormone replacement therapy
Phellinus lonicerinus
medicinal mushrooms
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting beta-catenin signaling
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 108, 页码: 724-733
作者:
Wang, Jixia
;
Qi, Huan
;
Zhang, Xiuli
;
Si, Wei
;
Xu, Fangfang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/06/20
Triple-negative breast cancer
Saikosaponin D
Radix Bupleuri
Wnt/beta-catenin
Saikosaponin d from radix bupleuri suppresses triple-negative breast cancer cell growth by targeting beta-catenin signaling
期刊论文
Biomedicine & pharmacotherapy, 2018, 卷号: 108, 页码: 724-733
作者:
Wang, Jixia
;
Qi, Huan
;
Zhang, Xiuli
;
Si, Wei
;
Xu, Fangfang
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/05/08
Triple-negative breast cancer
Saikosaponin d
Radix bupleuri
Wnt/beta-catenin
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
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