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上海药物研究所 [31]
海洋研究所 [4]
合肥物质科学研究院 [4]
西北高原生物研究所 [3]
过程工程研究所 [3]
兰州理工大学 [2]
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期刊论文 [59]
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2021 [59]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Transformer-Based Generative Model Accelerating the Development of Novel BRAF Inhibitors
期刊论文
ACS OMEGA, 2021, 卷号: 6, 期号: 49, 页码: 33864-33873
作者:
Yang, Lijuan
;
Yang, Guanghui
;
Bing, Zhitong
;
Tian, Yuan
;
Niu, Yuzhen
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  |  
浏览/下载:16/0
  |  
提交时间:2022/04/11
Distinct binding kinetics of E-, P- and L-selectins to CD44
期刊论文
FEBS JOURNAL, 2021, 页码: 18
作者:
Li LD(李林达)
;
Ding QH(丁奇寒)
;
Zhou J(周瑾)
;
Wu Y(武亿)
;
Zhang MK(张明坤)
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/12
binding epitope
binding kinetics
CD44
selectin
Characterization of a Haematococcus pluvialis Diacylglycerol Acyltransferase 1 and Its Potential in Unsaturated Fatty Acid-Rich Triacylglycerol Production
期刊论文
FRONTIERS IN PLANT SCIENCE, 2021, 卷号: 12, 页码: 16
作者:
Cui, Hongli
;
Xu, Wenxin
;
Zhu, Xiaoli
;
Zhao, Chunchao
;
Cui, Yulin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/08/13
Haematococcus pluvialis
type-I diacylglycerol acyltransferase
function characterization
esterified astaxanthin
triacylglycerol
genetic engineering
Bhimamycin J, a Rare Benzo[f]isoindole-dione Alkaloid from the Marine-Derived Actinomycete Streptomyces sp. MS180069
期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 页码: 7
作者:
Song, Fuhang
;
Yang, Na
;
Khalil, Zeinab G.
;
Salim, Angela A.
;
Han, Jiahui
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  |  
浏览/下载:67/0
  |  
提交时间:2021/12/02
marine-derived actinomycete
bhimamycin J
SARS-CoV-2
molecular docking
angiotensin converting enzyme2
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
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  |  
浏览/下载:96/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones
The Streptococcus agalactiae Ribose Binding Protein B (RbsB) Mediates Quorum Sensing Signal Uptake via Interaction with Autoinducer-2 Signals
期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2021, 卷号: 20, 期号: 5, 页码: 1285-1295
作者:
Fan Bolin
;
Pan Lixia
;
Wang Zhongliang
;
Eakapol, Wangkahart
;
Huang Yuchong
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/09/18
Streptococcus agalactiae
RbsB protein
circular dichroism (CD) spectroscopy
isothermal titration calorimetry(200) (ITC200)
molecular docking
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Isolation and characterization of phellodendronoside A, a new isoquinoline alkaloid glycoside with anti-inflammatory activity from Phellodendron chinense Schneid
期刊论文
FITOTERAPIA, 2021, 卷号: 154
作者:
Si, Yanpo
;
Li, Xiaofei
;
Guo, Tao
;
Wei, Wenjun
;
Zhang, Jubao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/17
Phellodendron chinense
Phellodendronoside A
Anti-inflammatory
MAPK pathway
Molecular docking
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