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中国医学科学院 北... [22]
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期刊论文 [22]
发表日期
2019 [7]
2018 [2]
2017 [3]
2016 [3]
2015 [4]
2014 [1]
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专题:中国医学科学院 北京协和医学院
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Components synergy between stilbenes and emodin derivatives contributes to hepatotoxicity induced by Polygonum multiflorum
期刊论文
2019, 页码: 1-11
作者:
Zhang Le
;
Liu Xiaoyi
;
Tu Can
;
Li Chunyu
;
Song Di
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
Thunb.
emodin-8-D-glucoside
idiosyncratic drug-induced liver injury
metabolomics
stilbene
A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study
期刊论文
2019, 卷号: 9, 期号: 10
作者:
He Shuaibing
;
Zhang Xuelian
;
Lu Shan
;
Zhu Ting
;
Sun Guibo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
DILI
Polygonum multiflorum Thunb
TCMs
Traditional Chinese Medicines
computational toxicology
drug-induced liver injury
hepatotoxicity
Herb-Induced Liver Injury: Phylogenetic Relationship, Structure-Toxicity Relationship, and Herb-Ingredient Network Analysis
期刊论文
2019, 卷号: 20, 期号: 15
作者:
He Shuaibing
;
Zhang Chenyang
;
Zhou Ping
;
Zhang Xuelian
;
Ye Tianyuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
HILI
hepatotoxicity
herb
herb-ingredient network
mechanism
phylogenetic tree
structure-toxicity relationship
Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased rats
期刊论文
2019, 卷号: 10, 期号: 6, 页码: 3477-3490
作者:
Tu, Can
;
Niu, Ming
;
Li, Chunyu
;
Liu, Zhenjie
;
He, Qin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine
期刊论文
2019, 卷号: 10, 页码: 458
作者:
Wu, Qihui
;
Cai, Chuipu
;
Guo, Pengfei
;
Chen, Meiling
;
Wu, Xiaoqin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/01/03
herb induced liver injury
consensus model
traditional chinese medicine
hepatotoxicity mechanism
in silico
An In Silico Model for Predicting Drug-Induced Hepatotoxicity
期刊论文
2019, 卷号: 20, 期号: 8
作者:
He, Shuaibing
;
Ye, Tianyuan
;
Wang, Ruiying
;
Zhang, Chenyang
;
Zhang, Xuelian
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
DILI
hepatotoxicity
in silico
machine learning
molecular descriptors
Xian-Ling-Gu-Bao induced inflammatory stress rat liver injury: Inflammatory and oxidative stress playing important roles
期刊论文
2019, 卷号: 239, 页码: 111910
作者:
Wu, Wenxiao
;
Wang, Ting
;
Sun, Bo
;
Liu, Dong
;
Lin, Zhi
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Xian Ling Gu Bao
Osteoarthritis
Hepatotoxicity
Inflammation factor
Oxidative stress
Hepatoprotective effect of rhein against methotrexate-induced liver toxicity
期刊论文
2018, 卷号: 834, 页码: 266-273
作者:
Bu, Tianci
;
Wang, Changyuan
;
Meng, Qiang
;
Huo, Xiaokui
;
Sun, Huijun
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Methotrexate
Diacerein
Rhein
Hepatotoxicity
Nuclear factor erythroid 2-related factor 2
Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes
期刊论文
2018, 卷号: 34, 期号: 1, 页码: 51-64
作者:
Kim, Jong Hyun
;
Wang, Min
;
Lee, Jaehun
;
Park, Han-Jin
;
Han, Chungseong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Drug screening
Hepatocytes
Human embryonic stem cells
Toxicity test
The chronic hepatotoxicity assessment of the herbal formula Zishen Yutai pill
期刊论文
2017, 卷号: 83, 页码: 81-88
作者:
Xing, Xiaoyan
;
Deng, Xuehong
;
Shi, Jinjin
;
Zhang, Meishuang
;
Sun, Guibo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Zishen Yutai pill
Herbal formula
Chronic hepatotoxicity
Polygoni multiflori Radix
No-observed-adverse-effect levels
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