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成都中医药大学 [8]
中国医学科学院 北京... [7]
山东大学 [6]
上海中医药大学 [6]
上海药物研究所 [5]
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期刊论文 [67]
发表日期
2019 [67]
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Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies
期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2019, 卷号: 16, 期号: 1, 页码: -
作者:
Xu, Ming
;
Yang, Qiuyuan
;
Xu, Lining
;
Rao, Ziyu
;
Cao, Dong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/09/10
Silver nanoparticles
Silver ion
Hepatotoxicity
Protein target
Glutathione S-transferase
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury
期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:
Hu, Dan-Dan
;
Zhao, Qi
;
Cheng, Yan
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/03/26
liver injury
metabolomics
PPAR alpha
acylcarnitines
Hepatoprotective effects of a traditional Chinese medicine formula against carbon tetrachloride-induced hepatotoxicity in vivo and in vitro
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 117, 页码: 8
作者:
Ren, Xia
;
Xin, Lan-Ting
;
Zhang, Meng-Qi
;
Zhao, Qing
;
Yue, Shi-Yun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Le-Cao-Shi formula
Acute liver injury
Hepatoprotective effect
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:
Yang, Mengbi
;
Ma, Jiang
;
Ruan, Jianqing
;
Ye, Yang
;
Fu, Peter Pi-Cheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Pyrrolizidine alkaloid N-oxides
Pyrrolizidine alkaloids
Pyrrolizidine alkaloid N-oxide toxicity
Biotransformation of pyrrolizidine alkaloid N-oxides
Microbiota biotransformation
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:
Zhao, Qi
;
Zhang, Ting
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
;
Wang, Yan
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/07/29
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 174, 页码: 353-362
作者:
Liang, Shengxian
;
Liang, Shaojun
;
Yin, Nuoya
;
Faiola, Francesco
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/10/21
Thyroid hormones (THs)
Polybrominated diphenyl ethers BDE-47/209
Human embryonic stem cells (ESCs)
Developmental hepatotoxicity
Endocrine-disrupting chemicals (EDCs)
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 1: Metabolic profiles from the liver-centric perspective
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 237, 页码: 81-91
作者:
Liu, Huan
;
Chen, Mingcang
;
Yin, Hao
;
Hu, Pei
;
Wang, Yangyang
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  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Yin-chen-hao tang
Liver
Metabolites
Liver injury
HPLC-Q-TOF
Carbon tetrachloride
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Liang, Wei-Qing
;
Xiao, Yao
;
Zhao, Qi
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/07/29
Pazopanib
hepatotoxicity
metabolomics
oxidative stress
ultra-performance liquid chromatography-electrospray ion source-quadrupole
time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Intervening Effects of Total Alkaloids of Corydalis saxicola Bunting on Rats With Antibiotic-Induced Gut Microbiota Dysbiosis Based on 16S rRNA Gene Sequencing and Untargeted Metabolomics Analyses
期刊论文
FRONTIERS IN MICROBIOLOGY, 2019, 卷号: 10, 页码: 18
作者:
Liu, Xi
;
Zheng, Hua
;
Lu, Rigang
;
Huang, Huimin
;
Zhu, Hongjia
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2019/10/14
antibiotic-induced gut microbiota dysbiosis
16S rRNA gene sequencing analysis
untargeted metabolomics
total alkaloids of Corydalis saxicola Bunting (TACS)
ultra-performance liquid chromatography-quadrupole time-of-flight/mass spectrometry
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